Impact of Platelet Count on Perioperative Bleeding in Patients With Cirrhosis Undergoing Surgical Treatments of Liver Cancer

Vincenzo Ronca, Matteo Barabino, Roberto Santambrogio, Enrico Opocher, James Hodson, Emanuela Bertolini, Simone Birocchi, Gaetano Piccolo, PierMaria Battezzati, Marco Cattaneo, Gian Marco Podda – 29 October 2021 – In patients with cirrhosis with severe thrombocytopenia (platelet count [PC] <50 × 109/L) and undergoing invasive procedures, it is common clinical practice to increase the PC with platelet transfusions or thrombopoietin receptor agonists to reduce the risk of major periprocedural bleeding.

Validation of Dynamic Aspartate‐to–Alanine Aminotransferase Ratio for Predicting Liver Disease Mortality

In‐Ae Song, Eun Sun Jang, Tak Kyu Oh – 28 October 2021 – The dynamic aspartate‐to–alanine aminotransferase ratio (dAAR) was developed recently to predict the risk of incident chronic liver disease among the Nordic adult population; however, the dAAR has not been externally validated in other ethnic cohorts. Therefore, we aimed to examine the predictive ability of dAAR for liver disease mortality in the South Korean adult population.

A Diagnostic Test Meta‐Analysis Evaluating Imaging‐Based and Blood Biomarker–Based Assessment Tools for Fibrosis After Liver Transplantation

Cheng Han Ng, Darren Jun Hao Tan, Xiong Chang Lim, Jie Ning Yong, Nicholas Syn, Gwyneth Shook Ting Soon, Daniel Q. Huang, Jieling Xiao, Grace En Hui Lim, Wen Hui Lim, Eunice Xiang Xuan Tan, Yock Young Dan, Mazen Noureddin, Mohammad Shadab Siddiqui, Mark D. Muthiah – 28 October 2021 – Early detection of liver graft fibrosis is crucial for risk stratification to identify patients for liver biopsy and timely treatment. However, diagnostic accuracy of noninvasive tests (NITs) remains unclear.

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