The 2020 Nobel Prize for Medicine or Physiology for the Discovery of Hepatitis C Virus: A Triumph of Curiosity and Persistence

Marc G. Ghany, Anna S.F. Lok, Jules L. Dienstag, Stephen M. Feinstone, Jay H. Hoofnagle, T. Jake Liang, Leonard B. Seeff, David E. Cohen, Jorge A. Bezerra, Raymond T. Chung – 29 March 2021 – The 2020 Nobel Prize in Medicine or Physiology was awarded to Drs. Harvey Alter, Michael Houghton, and Charles Rice for their contributions to the discovery and characterization of the hepatitis C virus (HCV). Their achievements represent a remarkable triumph of biomedical science which allowed the development of curative therapy for HCV, that will save countless lives.

LiverLearning®: 2021 Webinar: Simultaneous Liver Kidney Transplant: How Did We Do With the New Criteria?

In this one hour on-demand webinar, we will discuss how we arrived at the new organ allocation schema for simultaneous liver kidney (SLK) transplants by UNOS in partnership with our Transplant Nephrologists and the effect this has had on dual organ allocation and outcomes of SLK transplantation.Ryutaro Hirose Ryutaro Hirose, MD is professor and vice chair of clinical operations and value for the Department of Surgery at the University of California, San Francisco. He is an active liver, kidney and pancreas transplant surgeon.

Risk of HCC With Hepatitis B Viremia Among HIV/HBV‐Coinfected Persons in North America

H. Nina Kim, Craig W. Newcomb, Dena M. Carbonari, Jason A. Roy, Jessie Torgersen, Keri N. Althoff, Mari M. Kitahata, K. Rajender Reddy, Joseph K. Lim, Michael J. Silverberg, Angel M. Mayor, Michael A. Horberg, Edward R. Cachay, Gregory D. Kirk, Jing Sun, Mark Hull, M. John Gill, Timothy R. Sterling, Jay R. Kostman, Marion G. Peters, Richard D. Moore, Marina B. Klein, Vincent Lo Re, for the North American AIDS Cohort Collaboration on Research, Design of IeDEA – 28 March 2021

Albumin in Advanced Liver Diseases: The Good and Bad of a Drug!

Rakesh Kumar Jagdish, Jaswinder Singh Maras, Shiv Kumar Sarin – 26 March 2021 – Human serum albumin is the most abundant plasma protein, and it regulates diverse body functions. In patients with advanced and decompensated cirrhosis, serum albumin levels are low because of a reduction in the hepatocyte mass due to disease per se and multiple therapeutic interventions.

A Mouse Model of Cholangiocarcinoma Uncovers a Role for Tensin‐4 in Tumor Progression

Mickaël Di‐Luoffo, Sophie Pirenne, Thoueiba Saandi, Axelle Loriot, Claude Gérard, Nicolas Dauguet, Fátima Manzano‐Núñez, Natália Alves Souza Carvalhais, Florence Lamoline, Sabine Cordi, Katarzyna Konobrocka, Vitaline De Greef, Mina Komuta, Georg Halder, Patrick Jacquemin, Frédéric P. Lemaigre – 25 March 2021

Elective Surgery but not Transjugular Intrahepatic Portosystemic Shunt Precipitates Acute‐On‐Chronic Liver Failure

Johannes Chang, Avend Bamarni, Nina Böhling, Xin Zhou, Leah‐Marie Klein, Jonathan Meinke, Georg Daniel Duerr, Philipp Lingohr, Sven Wehner, Maximilian J. Brol, Jürgen K. Rockstroh, Jörg C. Kalff, Steffen Manekeller, Carsten Meyer, Ulrich Spengler, Christian Jansen, Vicente Arroyo, Christian P. Strassburg, Jonel Trebicka, Michael Praktiknjo – 25 March 2021 – Acute‐on‐chronic liver failure (ACLF) is a syndrome associated with organ failure and high short‐term mortality.

Tumor Necrosis Factor α–Induced Protein 8–Like 2 Alleviates Nonalcoholic Fatty Liver Disease Through Suppressing Transforming Growth Factor Beta–Activated Kinase 1 Activation

Yupeng Liu, Jingjing Song, Juan Yang, Jilin Zheng, Ling Yang, Jun Gao, Song Tian, Zhen Liu, Xiangbin Meng, Jian‐Cheng Wang, Zhifei Dai, Yi‐Da Tang – 25 March 2021

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