Practices and Perceptions of Living Donor Liver Transplantation, Nondirected Donation, and Liver Paired Exchange: A National Survey

Alyson Kaplan, Russell Rosenblatt, Whitney Jackson, Benjamin Samstein, Robert S. Brown – 2 December 2021 – Living donor liver transplantation (LDLT) remains underutilized in the United States. Barriers to LDLT and acceptance of nondirected living liver donation (ND‐LLD) and liver paired exchange (LPE) are unclear. The medical and surgical directors of 99 unique transplantation programs (56 LDLT programs and 43 non‐LDLT programs) were surveyed to gain insight into perceptions and practices of LDLT and types of donors utilized. The response rate was 84%.

Severe Alcohol‐Associated Hepatitis Is Associated With Worse Survival in Critically Ill Patients With Acute on Chronic Liver Failure

Kavish R. Patidar, Jennifer L. Peng, Harleen Kaur, Astin Worden, Carla D. Kettler, Francis Pike, Caitriona A. Buckley, Eric S. Orman, Archita P Desai, Lauren D. Nephew, Chandrashekhar A. Kubal, Samer Gawrieh, Naga Chalasani, Marwan S. Ghabril – 2 December 2021 – Differences in mortality between critically ill patients with severe alcohol‐associated hepatitis (sAH) and acute‐on‐chronic liver failure (ACLF) and non‐sAH ACLF (i.e., ACLF not precipitated by sAH) are unknown. Such differences are important, as they may inform on prognosis and optimal timing of liver transplantation (LT).

Secondary Prophylaxis of Gastric Variceal Bleeding: A Systematic Review and Network Meta‐Analysis

Karim T. Osman, Tarek Nayfeh, Ahmed M. Abdelfattah, Khaled Alabdallah, Bashar Hasan, Mohammed Firwana, Homam Alabaji, Lina Elkhabiry, Jehan Mousa, Larry J. Prokop, M. Hassan Murad, Fredric Gordon – 2 December 2021 – There is no clear consensus regarding the optimal approach for secondary prophylaxis of gastric variceal bleeding (GVB) in patients with cirrhosis. We conducted a systematic review and network meta‐analysis (NMA) to compare the efficacy of available treatments.

Reply

Andrew I. Aronsohn, Debika Bhattacharya, Timothy R. Morgan, David L. Wyles, Raymond T. Chung, Daniel P. McQuillen, AASLD‐IDSA HCV Guidance – 2 December 2021

Letter to the editor: Are clinical practice guidelines for hepatitis C by the American Association for the Study of Liver Diseases and Infectious Diseases Society of America evidence based? Financial conflicts of interest and assessment of quality of evid

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