Sleep Disturbance Is Associated With the Presence of Portosystemic Collaterals in Patients With Compensated Cirrhosis

Maya Balakrishnan, Caroline Falker, Samantha Conley, Maria Ciarleglio, Yanhong Deng, Nancy S. Redeker, Guadalupe Garcia‐Tsao – 2 February 2021 – Disturbed sleep is common among patients with cirrhosis. The extent to which this is associated with the different stages of compensated cirrhosis is unknown. This study examines whether the presence of portosystemic collaterals, an indicator of clinically significant portal hypertension, is associated with sleep disturbance in compensated cirrhosis.

Cirrhotic Cardiomyopathy Predicts Posttransplant Cardiovascular Disease: Revelations of the New Diagnostic Criteria

Manhal Izzy, Anna Soldatova, Xin Sun, Mounika Angirekula, Kristin Mara, Grace Lin, Kymberly D. Watt – 2 February 2021 – The diagnostic criteria for cirrhotic cardiomyopathy (CCM) were recently revised to reflect the contemporary advancements in echocardiographic technology. This study evaluates the prevalence of CCM, according to the new criteria, and its impact on posttransplant cardiovascular disease (CVD). This is a single‐center retrospective matched cohort study of liver transplantation (LT) recipients who underwent LT between January 1, 2008 and November 30, 2017.

Nuclear factor erythroid 2–related factor 2 and β‐Catenin Coactivation in Hepatocellular Cancer: Biological and Therapeutic Implications

Junyan Tao, Yekaterina Krutsenko, Akshata Moghe, Sucha Singh, Minakshi Poddar, Aaron Bell, Michael Oertel, Aatur D. Singhi, David Geller, Xin Chen, Amaia Lujambio, Silvia Liu, Satdarshan P. Monga – 1 February 2021

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