Dual Agonist of Farnesoid X Receptor and Takeda G Protein‐Coupled Receptor 5 Inhibits Hepatitis B Virus Infection In Vitro and In Vivo

Kiyoaki Ito, Akinori Okumura, Junko S. Takeuchi, Koichi Watashi, Rieko Inoue, Taeko Yamauchi, Kazumasa Sakamoto, Yukiko Yamashita, Yusuke Iguchi, Mizuho Une, Takaji Wakita, Kazuo Umezawa, Masashi Yoneda – 11 January 2021

LiverLearning®: 2021 Webinar: Practical Approach to Coagulation Management in Cirrhosis

Coagulation disorders in patients with cirrhosis present challenging situations for clinical providers. This one hour webinar will summarize the knowledge behind coagulation disorders in patients with cirrhosis, including the mixed and thrombosis prone model, limitations in current tests of hemostasis, and the dangers of excessive transfusion.

Cirrhosis Is Associated With High Mortality and Readmissions Over 90 Days Regardless of COVID‐19: A Multicenter Cohort

Jasmohan S. Bajaj, Guadalupe Garcia‐Tsao, Florence Wong, Scott W. Biggins, Patrick S. Kamath, Sara McGeorge, Michael Chew, Meredith Pearson, Jawaid Shaw, Anita Kalluri, Andrew Fagan, Amy Olofson, Maryam Moini, Randolph Rosa Rodriguez, K. Rajender Reddy – 10 January 2021

The Use of Rifaximin in Patients With Cirrhosis

Paolo Caraceni, Victor Vargas, Elsa Solà, Carlo Alessandria, Koos Wit, Jonel Trebicka, Paolo Angeli, Rajeshwar P. Mookerjee, François Durand, Elisa Pose, Aleksander Krag, Jasmohan S. Bajaj, Ulrich Beuers, Pere Ginès, for the Liverhope Consortium – 8 January 2021 – Rifaximin is an oral nonsystemic antibiotic with minimal gastrointestinal absorption and broad‐spectrum antibacterial activity covering both gram‐positive and gram‐negative organisms.

Clinical Presentation and Gene Expression of Acute Alcohol‐Induced Microvesicular Steatosis Mimicking Alcoholic Hepatitis

Laurent Spahr, Nicolas Lanthier, Mathieu Tihy, Jean‐Louis Frossard, Laura Rubbia‐Brandt, Nicolas Goossens – 8 January 2021 – Acute alcoholic microvesicular steatosis (MIC) may complicate heavy alcohol intake and present as alcoholic hepatitis (AH) syndrome. However, detailed clinical, biological, and histologic data associated with MIC are scarce. We compared the clinical presentation, histologic features, and hepatic transcriptomic of patients presenting with AH due to either MIC or severe alcoholic steatohepatitis (ASH).

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