Cost‐Effectiveness of Primary Liver Transplantation Versus Hepatoportoenterostomy in the Management of Biliary Atresia in the United States

Vikram K. Raghu, James E. Squires, Douglas B. Mogul, Robert H. Squires, Patrick J. McKiernan, George V. Mazariegos, Kenneth J. Smith – 17 January 2021 – Biliary atresia (BA) is the leading indication to perform a pediatric liver transplantation (LT). Timely hepatoportoenterostomy (HPE) attempts to interrupt the natural history and allow for enteric bile flow; however, most patients who are treated with HPE require LT by the age of 10 years. We determined the cost‐effectiveness of foregoing HPE to perform primary LT (pLT) in children with BA compared with standard‐of‐care HPE management.

Sex and Menopause Modify the Effect of Single Nucleotide Polymorphism Genotypes on Fibrosis in NAFLD

Kara Wegermann, Melanie E. Garrett, Jiayin Zheng, Andrea Coviello, Cynthia A. Moylan, Manal F. Abdelmalek, Shein‐Chung Chow, Cynthia D. Guy, Anna Mae Diehl, Allison Ashley‐Koch, Ayako Suzuki – 17 January 2021 – The development of fibrosis in nonalcoholic fatty liver disease (NAFLD) is influenced by genetics, sex, and menopausal status, but whether genetic susceptibility to fibrosis is influenced by sex and reproductive status is unclear.

Endoscopic Cyanoacrylate Injection Versus Balloon‐Occluded Retrograde Transvenous Obliteration for Prevention of Gastric Variceal Bleeding: A Randomized Controlled Trial

Xuefeng Luo, Tong Xiang, Junchao Wu, Xiaoze Wang, Yongjun Zhu, Xiaotan Xi, Yuling Yan, Jinlin Yang, Juan Carlos García‐Pagán, Li Yang – 13 January 2021

The Growing Burden of Disability Related to Chronic Liver Disease in the United States: Data From the Global Burden of Disease Study 2007‐2017

James M. Paik, Pegah Golabi, Youssef Younossi, Nazaneen Saleh, Annan Nhyira, Zobair M. Younossi – 13 January 2021 – Chronic liver disease (CLD) causes significant morbidity and mortality in the United States with regional variations. Comparable and consistent state‐level measures of CLD‐related morbidity and disability among U.S. states have not been well studied.

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