DNA Methylation Markers for Detection of Cholangiocarcinoma: Discovery, Validation, and Clinical Testing in Biliary Brushings and Plasma
Ju Dong Yang, Hassan Ghoz, Mohammed M. Aboelsoud, William R. Taylor, Tracy C. Yab, Calise K. Berger, Xiaoming Cao, Patrick H. Foote, Nasra H. Giama, Emily G. Barr Fritcher, Douglas W. Mahoney, Catherine D. Moser, Thomas C. Smyrk, Benjamin R. Kipp, Gregory J. Gores, Lewis R. Roberts, John B. Kisiel – 2 May 2021 – Cholangiocarcinoma (CCA) has poor prognosis due to late‐stage, symptomatic presentation. Altered DNA methylation markers may improve diagnosis of CCA.