Reduced Clot Stability by Thromboelastography as a Potential Indicator of Procedure‐Related Bleeding in Decompensated Cirrhosis

Alberto Zanetto, Henry M. Rinder, Marco Senzolo, Paolo Simioni, Guadalupe Garcia‐Tsao – 12 December 2020 – In patients with decompensated cirrhosis, procedure‐related bleeding is a potentially lethal complication. Routine coagulation tests such as international normalized ratio and platelet count do not predict bleeding risk. We investigated whether thromboelastography (TEG) can identify patients with cirrhosis who are at risk of procedure‐related bleeding.

Adenosine Diphosphate and the P2Y13 Receptor Are Involved in the Autophagic Protection of Ex Vivo Perfused Livers From Fasted Rats: Potential Benefit for Liver Graft Preservation

Bérengère Papegay, Vincent Nuyens, Adelin Albert, Mustapha Cherkaoui‐Malki, Pierre Andreoletti, Oberdan Leo, Véronique Kruys, Jean G. Boogaerts, Joseph Vamecq – 11 December 2020 – Studies on how to protect livers perfused ex vivo can help design strategies for hepatoprotection and liver graft preservation. The protection of livers isolated from 24‐hour versus 18‐hour starved rats has been previously attributed to autophagy, which contributes to the energy‐mobilizing capacity ex vivo. Here, we explored the signaling pathways responsible for this protection.

Posttransplant Outcomes in Older Patients With Hepatocellular Carcinoma Are Driven by Non–Hepatocellular Carcinoma Factors

Nia Adeniji, Vinodhini Arjunan, Vijay Prabhakar, Ajitha Mannalithara, Tara Ghaziani, Aijaz Ahmed, Paul Kwo, Mindie Nguyen, Marc L. Melcher, Ronald W. Busuttil, Sander S. Florman, Brandy Haydel, Richard M. Ruiz, Goran B. Klintmalm, David D. Lee, C. Burcin Taner, Maarouf A. Hoteit, Elizabeth C. Verna, Karim J. Halazun, Amit D. Tevar, Abhinav Humar, William C. Chapman, Neeta Vachharajani, Federico Aucejo, Trevor L. Nydam, James F. Markmann, Constance Mobley, Mark Ghobrial, Alan N. Langnas, Carol A. Carney, Jennifer Berumen, Gabriel T. Schnickel, Debra L. Sudan, Johnny C.

Subscribe to