Fecal Microbiota Transplant in Cirrhosis Reduces Gut Microbial Antibiotic Resistance Genes: Analysis of Two Trials

Jasmohan S. Bajaj, Amirhossein Shamsaddini, Andrew Fagan, Richard K. Sterling, Edith Gavis, Alexander Khoruts, Michael Fuchs, Hannah Lee, Masoumeh Sikaroodi, Patrick M. Gillevet – 21 November 2020 – Antibiotic resistance leads to poor outcomes in cirrhosis. Fecal microbiota transplant (FMT) is associated with reduction in antibiotic resistance gene (ARG) burden in patients without cirrhosis; however, the impact in cirrhosis is unclear.

Bleeding Outcomes Following Transesophageal Echocardiography in Patients With Cirrhosis and Esophageal Varices

Jordan S. Sack, Michael Li, Stephen D. Zucker – 21 November 2020 – Despite scant evidence, current guidelines indicate that esophageal varices are a relative contraindication to transesophageal echocardiography (TEE). The aim of this study is to compare the risk of gastrointestinal bleeding following TEE among cirrhotic patients with and without endoscopically‐documented esophageal varices. This is a retrospective analysis of patients with cirrhosis who underwent upper endoscopy within 4 years of TEE at five institutions between January 2000 and March 2020.

Factors Associated With Hepatitis A Mortality During Person‐to‐Person Outbreaks: A Matched Case–Control Study—United States, 2016‐2019

Megan G. Hofmeister, Jian Xing, Monique A. Foster, Ryan J. Augustine, Cole Burkholder, Jim Collins, Shannon McBee, Erica D. Thomasson, Douglas Thoroughman, Mark K. Weng, Philip R. Spradling – 20 November 2020

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