Real‐World Effectiveness of Obeticholic Acid in Patients with Primary Biliary Cholangitis

Surain B. Roberts, Marwa Ismail, Gowthami Kanagalingam, Andrew L. Mason, Mark G. Swain, Catherine Vincent, Eric M. Yoshida, Cynthia Tsien, Jennifer A. Flemming, Harry L.A. Janssen, Gideon M. Hirschfield, Bettina E. Hansen, Aliya F. Gulamhusein, the Canadian Network for Autoimmune Liver Disease – 6 July 2020 – Patients with primary biliary cholangitis (PBC) with incomplete response to ursodeoxycholic acid are at risk of disease progression and need additional therapy.

#LiverTwitter: An Emerging Tool for Liver Education and Research

Adam E. Mikolajczyk, Nneka Ufere, Anthony C. Breu, Neehar D. Parikh, Guadalupe Garcia‐Tsao, Elliot B. Tapper – 5 July 2020 – #LiverTwitter has emerged as an academic forum that has begun to advance the field of hepatology by disseminating content on chronic liver diseases to a global audience. This article summarizes the content presented in a panel discussion at the 2019 Liver Meeting by highlighting the perspectives of several key types of participants in Twitter: the trainee, the medical educator, the divisional account, the scientific journal, and the passive participant.

Definition and Prospective Assessment of Functional Recovery After Liver Transplantation: A New Objective Consensus‐Based Metric for Safe Discharge

Raffaele Brustia, Emmanuel Boleslawski, Antoine Monsel, Louise Barbier, Sébastien Dharancy, René Adam, Jérôme Dumortier, Mickaël Lesurtel, Filomena Conti, Olivier Scatton, Groupe de Recherche Français en Greffe de Foie (GReF²) and the Association de Chirurgie Hépato‐Pancréato‐Biliaire et Transplantation (ACHBT) Collaborative Group – 4 July 2020 – Standardized discharge criteria are critical to reduce premature discharge and avoid unnecessary hospital stays. No such criteria exist for patients undergoing liver transplantation (LT).

Validation of a Simple Quality‐of‐Life Score for Identification of Minimal and Prediction of Overt Hepatic Encephalopathy

Mette Munk Lauridsen, Peter Jepsen, Charlotte Wilhelmina Wernberg, Ove B. Schaffalitzky de Muckadell, Jasmohan S. Bajaj, Hendrik Vilstrup – 3 July 2020 – Minimal hepatic encephalopathy (MHE) is underdiagnosed because most clinics refrain from psychometric testing. Diagnostic activities need to go up so patients with MHE can get the treatment their condition requires. The sickness impact profile questionnaire for covert hepatic encephalopathy (SIPCHE) score is based on quality‐of‐life outcomes and has been proposed as a simple, patient‐administered diagnostic score for grade 1 and MHE.

Characterization and Proteome of Circulating Extracellular Vesicles as Potential Biomarkers for NASH

Davide Povero, Hirokazu Yamashita, Wenhua Ren, Mani G. Subramanian, Robert P. Myers, Akiko Eguchi, Douglas A. Simonetto, Zachary D. Goodman, Stephen A. Harrison, Arun J. Sanyal, Jaime Bosch, Ariel E. Feldstein – 3 July 2020 – Nonalcoholic fatty liver disease (NAFLD) is currently one of most common forms of chronic liver disease globally.

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