Gut Microbes Take It to the Next Level? First Insights Into Farnesoid X Receptor Agonists of Microbial Origin
Martin Lenicek, Steven W.M. Olde Damink, Frank G. Schaap – 10 July 2020
Martin Lenicek, Steven W.M. Olde Damink, Frank G. Schaap – 10 July 2020
9 July 2020
Maria Abbondanza Pantaleo, Massimo Del Gaudio, Matteo Ravaioli, Matteo Cescon, Margherita Nannini – 8 July 2020
Deepti Abbey, Susannah Elwyn, Nicholas J. Hand, Kiran Musunuru, Daniel J. Rader – 8 July 2020 – Establishment of a physiologically relevant human hepatocyte‐like cell system for in vitro translational research has been hampered by the limited availability of cell models that accurately reflect human biology and the pathophysiology of human disease. Here we report a robust, reproducible, and scalable protocol for the generation of hepatic organoids from human induced pluripotent stem cells (hiPSCs) using short exposure to nonengineered matrices.
Mark Antkowiak, Richard M. Green – 7 July 2020
Mark Antkowiak, Richard M. Green – 7 July 2020
Isabelle Chemin, Flor H. Pujol, Caroline Scholtès, Carmen L. Loureiro, Fouzia Amirache, Massimo Levrero, Fabien Zoulim, Jimena Pérez‐Vargas, François‐Loïc Cosset – 6 July 2020
Marco Spada, Roberta Angelico, Chiara Grimaldi, Paola Francalanci, Maria Cristina Saffioti, Andrea Rigamonti, Rosanna Pariante, Roberto Bianchi, Carlo Dionisi Vici, Manila Candusso, Giuseppe Maggiore – 6 July 2020
Surain B. Roberts, Marwa Ismail, Gowthami Kanagalingam, Andrew L. Mason, Mark G. Swain, Catherine Vincent, Eric M. Yoshida, Cynthia Tsien, Jennifer A. Flemming, Harry L.A. Janssen, Gideon M. Hirschfield, Bettina E. Hansen, Aliya F. Gulamhusein, the Canadian Network for Autoimmune Liver Disease – 6 July 2020 – Patients with primary biliary cholangitis (PBC) with incomplete response to ursodeoxycholic acid are at risk of disease progression and need additional therapy.
Nwe Ni Than, Jose Guillain Cataluna, Avik Majumdar – 6 July 2020