Lysyl Oxidase (LOX) Family Members: Rationale and Their Potential as Therapeutic Targets for Liver Fibrosis
Wei Chen, Aiting Yang, Jidong Jia, Yury V. Popov, Detlef Schuppan, Hong You – 16 March 2020 – The cross‐linking of structural extracellular matrix (ECM) components, especially fibrillar collagens and elastin, is strongly implicated in fibrosis progression and resistance to fibrosis reversal.