Analysis of Liver Resection Versus Liver Transplantation on Outcome of Small Intrahepatic Cholangiocarcinoma and Combined Hepatocellular‐Cholangiocarcinoma in the Setting of Cirrhosis

Eleonora De Martin, Michael Rayar, Nicolas Golse, Margot Dupeux, Maximiliano Gelli, Viviane Gnemmi, Marc Antoine Allard, Daniel Cherqui, Antonio Sa Cunha, Rene Adam, Audrey Coilly, Teresa Maria Antonini, Catherine Guettier, Didier Samuel, Karim Boudjema, Emmanuel Boleslawski, Eric Vibert – 24 February 2020 – This multicenter study compares the outcomes of patients with cirrhosis undergoing liver transplantation (LT) or liver resection (LR) between January 2002 and July 2015 who had intrahepatic cholangiocarcinoma (iCCA) or combined hepatocellular‐cholangiocarcinoma (cHCC‐CCA) found incident

Hemostatic Alterations in Patients With Cirrhosis: From Primary Hemostasis to Fibrinolysis

Maxime G. Zermatten, Montserrat Fraga, Darius Moradpour, Debora Bertaggia Calderara, Alessandro Aliotta, Guido Stirnimann, Andrea De Gottardi, Lorenzo Alberio – 23 February 2020 – In the setting of liver cirrhosis (LC), profound hemostatic changes occur, which affect primary hemostasis, coagulation, and fibrinolysis. They involve prohemorrhagic and prothrombotic alterations at each of these steps. Patients with cirrhosis exhibit multifactorial thrombocytopenia and in vitro thrombocytopathy, counterbalanced by increased von Willebrand factor.

Hemostatic Alterations in Patients With Cirrhosis: From Primary Hemostasis to Fibrinolysis

Maxime G. Zermatten, Montserrat Fraga, Darius Moradpour, Debora Bertaggia Calderara, Alessandro Aliotta, Guido Stirnimann, Andrea De Gottardi, Lorenzo Alberio – 23 February 2020 – In the setting of liver cirrhosis (LC), profound hemostatic changes occur, which affect primary hemostasis, coagulation, and fibrinolysis. They involve prohemorrhagic and prothrombotic alterations at each of these steps. Patients with cirrhosis exhibit multifactorial thrombocytopenia and in vitro thrombocytopathy, counterbalanced by increased von Willebrand factor.

Inflammation‐Induced Long Intergenic Noncoding RNA (LINC00665) Increases Malignancy Through Activating the Double‐Stranded RNA–Activated Protein Kinase/Nuclear Factor Kappa B Pathway in Hepatocellular Carcinoma

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