Cardiac and Liver Disease in Children: Implications for Management Before and After Liver Transplantation

Nicola D. Ruth, Nigel E. Drury, James Bennett, Deirdre A. Kelly – 24 December 2019 – There is close interaction between the functions of the liver and heart affecting the presentation, diagnosis, and outcome of acute and chronic cardiac and liver disease. Conditions affecting both organ systems should be considered when proposing transplantation because the interaction between cardiac disease and liver disease has implications for diagnosis, management, selection for transplantation, and, ultimately, for longterm outcomes after liver transplantation (LT).

Posttransplant Complications Predict Alcohol Relapse in Liver Transplant Recipients

Toshihiro Kitajima, Shunji Nagai, Antu Segal, Michelle Magee, Shaundra Blackburn, Donna Ellithorpe, Siri Yeddula, Yusuf Qadeer, Atsushi Yoshida, Dilip Moonka, Kimberly Brown, Marwan S. Abouljoud – 24 December 2019 – Alcohol relapse after liver transplantation (LT) in patients with alcohol‐related liver disease (ALD) is a major challenge. Although its association with pretransplant psychosocial factors was extensively studied, the impacts of posttransplant courses on alcohol relapse have not been well investigated.

Endogenous Interleukin 18 Suppresses Liver Regeneration After Hepatectomy in Mice

Tao Ma, Yibo Zhang, Mengyi Lao, Wen Chen, Qida Hu, Xiao Zhi, Zhiliang Chen, Xueli Bai, Xiaowei Dang, Tingbo Liang – 24 December 2019 – The comprehensive role of interleukin (IL) 18 during liver regeneration is barely studied. Our aim is to evaluate the role of IL18 in liver regeneration after partial hepatectomy (PH) in mice. The expression profile of IL18 in the liver and the gut after 70% PH was measured. Liver samples after 70% and 85% PH from IL18 knockout (IL18−/−) mice and wild type (WT) mice were collected for comparison of liver regeneration.

Model for End‐Stage Liver Disease With Additional Criteria to Predict Short‐Term Mortality in Severe Flares of Chronic Hepatitis B

James Fung, Lung‐Yi Mak, Albert Chi‐Yan Chan, Kenneth Siu‐Ho Chok, Tiffany Cho‐Lam Wong, Tan‐To Cheung, Wing‐Chiu Dai, Sui‐Ling Sin, Wong‐Hoi She, Ka‐Wing Ma, Wai‐Kay Seto, Ching‐Lung Lai, Chung‐Mau Lo, Man‐Fung Yuen – 23 December 2019

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