Letter to the Editor: The Association Between Diabetes and Hepatocellular Carcinoma in Patients With Cirrhosis Caused by Nonalcoholic Fatty Liver Disease
Xinxing Tantai, Na Liu, Jinhai Wang – 6 January 2020
Lymphoepithelioma‐Like Carcinomas: A Rare Variant of Cholangiocarcinoma
Austin Lin, Lindsay Alpert, John Hart, Christopher Chapman, Anjana A. Pillai – 6 January 2020
Applying Machine Learning in Liver Disease and Transplantation: A Comprehensive Review
Ashley Spann, Angeline Yasodhara, Justin Kang, Kymberly Watt, Bo Wang, Anna Goldenberg, Mamatha Bhat – 6 January 2020 – Machine learning (ML) utilizes artificial intelligence to generate predictive models efficiently and more effectively than conventional methods through detection of hidden patterns within large data sets. With this in mind, there are several areas within hepatology where these methods can be applied. In this review, we examine the literature pertaining to machine learning in hepatology and liver transplant medicine.
Liver Disease in Pregnancy: What's New
Carla W. Brady – 6 January 2020 – Liver disease in pregnancy may present as a disorder that is unique to pregnancy or as an acute or chronic liver disease occurring coincidentally in pregnancy. Hepatic diseases that are unique to pregnancy include hyperemesis gravidarum; preeclampsia/eclampsia; the syndrome of hemolysis, elevated liver enzymes, and low platelets; intrahepatic cholestasis of pregnancy; and acute fatty liver of pregnancy.
Lymphoepithelioma‐Like Carcinomas: A Rare Variant of Cholangiocarcinoma
Austin Lin, Lindsay Alpert, John Hart, Christopher Chapman, Anjana A. Pillai – 6 January 2020
The Transcription Factor Promyelocytic Leukemia Zinc Finger Protein Is Associated With Expression of Liver‐Homing Receptors on Human Blood CD56bright Natural Killer Cells
Leonard U. Hess, Glòria Martrus, Annerose E. Ziegler, Annika E. Langeneckert, Wilhelm Salzberger, Hanna Goebels, Adrian F. Sagebiel, Sven H. Hagen, Tobias Poch, Gevitha Ravichandran, Martina Koch, Christoph Schramm, Karl J. Oldhafer, Lutz Fischer, Gisa Tiegs, Laura Richert, Madeleine J. Bunders, Sebastian Lunemann, Marcus Altfeld – 6 January 2020 – The transcription factor promyelocytic leukemia zinc finger protein (PLZF) is involved in the development of natural killer (NK) cells and innate lymphoid cells, including liver‐resident NK cells in mice.
Liver Disease in Pregnancy: What's New
Carla W. Brady – 6 January 2020 – Liver disease in pregnancy may present as a disorder that is unique to pregnancy or as an acute or chronic liver disease occurring coincidentally in pregnancy. Hepatic diseases that are unique to pregnancy include hyperemesis gravidarum; preeclampsia/eclampsia; the syndrome of hemolysis, elevated liver enzymes, and low platelets; intrahepatic cholestasis of pregnancy; and acute fatty liver of pregnancy.
Small but Mighty: Platelets in NASH and Other Chronic Liver Diseases
Moira B. Hilscher, Vijay H. Shah – 5 January 2020
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Ju Dong Yang, Kristin C. Mara, Gregory J. Gores, Lewis R. Roberts – 4 January 2020
Assessment of Rapid Hepatic Glycogen Synthesis in Humans Using Dynamic 13C Magnetic Resonance Spectroscopy
Stefan Stender, Vlad G. Zaha, Craig R. Malloy, Jessica Sudderth, Ralph J. DeBerardinis, Jae Mo Park – 4 January 2020 – Carbon‐13 magnetic resonance spectroscopy (MRS) following oral intake of 13C‐labeled glucose is the gold standard for imaging glycogen metabolism in humans. However, the temporal resolution of previous studies has been >13 minutes. Here, we describe a high‐sensitivity 13C MRS method for imaging hepatic glycogen synthesis with a temporal resolution of 1 minute or less.