Neil Mehta, Jennifer L. Dodge, John P. Roberts, Ryutaro Hirose, Francis Y. Yao – 13 December 2018 – High alpha‐fetoprotein (AFP) > 1,000 ng/mL is associated with poor outcomes after liver transplantation (LT) for hepatocellular carcinoma (HCC). A new national policy has been implemented for AFP > 1,000 ng/mL requiring a decrease to < 500 ng/mL before LT, but there is a paucity of data on the optimal AFP threshold before LT.

Li Chen, David A. Brenner, Tatiana Kisseleva – 13 December 2018 – Hepatic fibrosis results from chronic injury and inflammation in the liver and leads to cirrhosis, liver failure, and portal hypertension. Understanding the molecular mechanisms underlying hepatic fibrosis has advanced the prospect of developing therapies for regression of the disease.

Elizabeth B. Rand – 12 December 2018

Nataliya Razumilava, Junya Shiota, Nureen H. Mohamad Zaki, Ramon Ocadiz‐Ruiz, Christine M. Cieslak, Kais Zakharia, Benjamin L. Allen, Gregory J. Gores, Linda C. Samuelson, Juanita L. Merchant – 11 December 2018 – Hedgehog (HH) signaling participates in hepatobiliary repair after injury and is activated in patients with cholangiopathies. Cholangiopathies are associated with bile duct (BD) hyperplasia, including expansion of peribiliary glands, the niche for biliary progenitor cells.

11 December 2018

Tawfik Khoury, Muhammad Massarwa, Saleh Daher, Ariel A. Benson, Wadi Hazou, Eran Israeli, Harold Jacob, Julia Epstein, Rifaat Safadi – 10 December 2018 – There are limited efficacious therapeutic options for management of gastric variceal bleeding. Treatment modalities include transjugular intrahepatic portosystemic shunt, surgical shunts, and endoscopic interventions, including the recent advancement of endoscopic ultrasound (EUS)‐guided coiling.

Guadalupe Garcia‐Tsao – 10 December 2018

John Ong, Carla Swift – 10 December 2018

10 December 2018

Sanjay Kumar Yadav, Neeraj Saraf, Narendra S. Choudhary, Jayant Kumar Sah, Sujeet Kumar Sah, Amit Rastogi, Prashant Bhangui, Sanjiv Saigal, Arvinder Singh Soin – 8 December 2018 – Acute‐on‐chronic liver failure (ACLF) is a syndrome characterized by acute decompensation of previously diagnosed or undiagnosed liver disease with organ failure(s) with high short‐term mortality. This study was conducted to report the outcomes of living donor liver transplantation (LDLT) in ACLF and assess the survival benefit of liver transplantation (LT) in these patients.