Patient‐reported outcomes in cirrhosis: A scoping review of the literature

Elliot B. Tapper, Fasiha Kanwal, Sumeet K. Asrani, Chanda Ho, Nadia Ovchinsky, John Poterucha, Avegail Flores, Judith E. Smith, Victor Ankoma‐Sey, Bruce Luxon, Michael L. Volk – 22 December 2017 – Patients with cirrhosis seek improvement in their symptoms, functioning, quality of life, and satisfaction with the care they receive. However, these patient‐reported outcomes (PROs) are not routinely measured for clinical care, research, or quality improvement.

Ligation versus no ligation of spontaneous portosystemic shunts during liver transplantation: Audit of a prospective series of 66 consecutive patients

Concepcion Gomez Gavara, Prashant Bhangui, Chady Salloum, Michael Osseis, Francesco Esposito, Toufic Moussallem, Eylon Lahat, Liliana Fuentes, Philippe Compagnon, Norbert Ngongang, Chetana Lim, Daniel Azoulay – 21 December 2017 – The management of large spontaneous portosystemic shunt (SPSS) during liver transplantation (LT) is a matter of debate. The aim of this study is to compare the short‐term and longterm outcomes of SPSS ligation versus nonligation during LT, when both options are available.

Increased expression of GATA zinc finger domain containing 1 through gene amplification promotes liver cancer by directly inducing phosphatase of regenerating liver 3

Wei Sun, Yanquan Zhang, Ka Chun Wong, Ken Liu, Yidong Yang, Bin Wu, Joanna H.M. Tong, Anthony W.H. Chan, Henry L.Y. Chan, Jun Yu – 21 December 2017 – We identified that GATA zinc finger domain containing 1 (GATAD1), a transcriptional factor, was significantly up‐regulated in hepatocellular carcinoma (HCC) through gene amplification. We demonstrated the critical role, molecular mechanisms, and clinical implications of GATAD1 as a novel oncogenic factor in HCC. We found that GATAD1 protein was expressed in 76.6% of primary HCCs (85/111) but silenced in normal liver tissues.

Subscribe to