Marianne Ziol, Nicolas Poté, Giuliana Amaddeo, Alexis Laurent, Jean‐Charles Nault, Frédéric Oberti, Charlotte Costentin, Sophie Michalak, Mohamed Bouattour, Claire Francoz, Georges Philippe Pageaux, Jeanne Ramos, Thomas Decaens, Alain Luciani, Boris Guiu, Valérie Vilgrain, Christophe Aubé, Jonathan Derman, Cécile Charpy, Jessica Zucman‐Rossi, Nathalie Barget, Olivier Seror, Nathalie Ganne‐Carrié, Valérie Paradis, Julien Calderaro – 27 December 2017 – We recently identified a histological subtype of hepatocellular carcinoma (HCC), designated as “macrotrabecular‐massive” (MTM‐HCC) and associa

Alix P. M. Matton, Laura C. Burlage, Rianne van Rijn, Yvonne de Vries, Shanice A. Karangwa, Maarten W. Nijsten, Annette S. H. Gouw, Janneke Wiersema‐Buist, Jelle Adelmeijer, Andrie C. Westerkamp, Ton Lisman, Robert J. Porte – 27 December 2017 – Normothermic machine perfusion (NMP) enables viability assessment of donor livers prior to transplantation. NMP is frequently performed by using human blood products including red blood cells (RBCs) and fresh frozen plasma (FFP).

Patrik Nasr, Simone Ignatova, Stergios Kechagias, Mattias Ekstedt – 27 December 2017 – Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease in the world. The complete natural history of NAFLD is unknown because few high‐quality follow‐up studies have been conducted. Our aim was to find variables predicting disease severity through an extended follow‐up with serial biopsies.

Chirag Nepal, Colm J. O'Rourke, Douglas V.N.P. Oliveira, Andrzej Taranta, Steven Shema, Prson Gautam, Julien Calderaro, Andrew Barbour, Chiara Raggi, Krister Wennerberg, Xin W. Wang, Anja Lautem, Lewis R. Roberts, Jesper B. Andersen – 26 December 2017 – Intrahepatic cholangiocarcinoma remains a highly heterogeneous malignancy that has eluded effective patient stratification to date. The extent to which such heterogeneity can be influenced by individual driver mutations remains to be evaluated.

Nipun Verma, Amritjyot Kaur, Ratiram Sharma, Ashish Bhalla, Navneet Sharma, Arka De, Virendra Singh – 26 December 2017 – Decompensated cirrhosis (DC) carries a high mortality. Liver transplantation (LT) is the treatment of choice; however, the limited availability of donor organs has resulted in high waitlist mortality. The present study investigated the impact of multiple courses of granulocyte‐colony stimulating factor (G‐CSF) with or without growth hormone (GH) in these patients.

R. Cutler Quillin, James V. Guarrera – 26 December 2017 – A finite supply of donor organs has led many transplant centers to accept marginal liver allografts with increasing frequency. These allografts may be at higher risk of primary nonfunction, early allograft dysfunction, and other recipient complications following liver transplantation. Machine perfusion preservation is an emerging technology that limits ischemia/reperfusion injury associated with preservation and may lead to improved outcomes following transplantation.

Jasmohan S. Bajaj, Phillip B. Hylemon – 22 December 2017

Audrey Winter, Jean‐Pierre Daurès, Paul Landais – 22 December 2017

Takeo Yoshihara, Ryotaro Sakamori, Kunimaro Furuta, Minoru Shigekawa, Ryoko Yamada, Takahiro Kodama, Hayato Hikita, Takayuki Yakushijin, Tomohide Tatsumi, Yasushi Sakata, Hidetoshi Eguchi, Yoshiki Sawa, Tetsuo Takehara – 22 December 2017

Elliot B. Tapper, Fasiha Kanwal, Sumeet K. Asrani, Chanda Ho, Nadia Ovchinsky, John Poterucha, Avegail Flores, Judith E. Smith, Victor Ankoma‐Sey, Bruce Luxon, Michael L. Volk – 22 December 2017 – Patients with cirrhosis seek improvement in their symptoms, functioning, quality of life, and satisfaction with the care they receive. However, these patient‐reported outcomes (PROs) are not routinely measured for clinical care, research, or quality improvement.