Budd‐chiari syndrome causing acute liver failure: A multicenter case series

Justin Parekh, Vlad M. Matei, Alejandro Canas‐Coto, Daniel Friedman, William M. Lee, the Acute Liver Failure Study Group – 22 September 2016 – Budd‐Chiari syndrome (BCS) is a rare disease resulting from obstruction of the hepatic venous outflow tract that typically presents with abdominal pain, jaundice, and ascites without frank liver failure. However, BCS may also evolve more rapidly to acute liver failure (ALF). In this study, we describe the clinical features, treatment, and outcomes of ALF due to BCS and compare our results with those in the published literature.

Liver transplantation after share 35: Impact on pretransplant and posttransplant costs and mortality

Clara T. Nicolas, Scott L. Nyberg, Julie K. Heimbach, Kymberly Watt, Harvey S. Chen, Matthew A. Hathcock, Walter K. Kremers – 22 September 2016 – Share 35 was implemented in 2013 to direct livers to the most urgent candidates by prioritizing Model for End‐Stage Liver Disease (MELD) ≥ 35 patients. We aim to evaluate this policy's impact on costs and mortality. Our study includes 834 wait‐listed patients and 338 patients who received deceased donor, solitary liver transplants at Mayo Clinic between January 2010 and December 2014.

Biliary atresia: Indications and timing of liver transplantation and optimization of pretransplant care

Shikha S. Sundaram, Cara L. Mack, Amy G. Feldman, Ronald J. Sokol – 21 September 2016 – Biliary atresia (BA) is a progressive, fibro‐obliterative disorder of the intrahepatic and extrahepatic bile ducts in infancy. The majority of affected children will eventually develop end‐stage liver disease and require liver transplantation (LT). Indications for LT in BA include failed Kasai portoenterostomy, significant and recalcitrant malnutrition, recurrent cholangitis, and the progressive manifestations of portal hypertension.

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