Lei Zhao, Linda L. Wong, Xuetao Shi, Junfang Ji – 11 January 2016

George Papatheodoridis, Ioannis Vlachogiannakos, Evangelos Cholongitas, Karsten Wursthorn, Christos Thomadakis, Giota Touloumi, Jörg Petersen – 11 January 2016 – The possibility of safe discontinuation of therapy with nucleos(t)ide analogues (NAs) remains one of the most controversial topics in the management of chronic hepatitis B. Therefore, we systematically reviewed the existing data on NA discontinuation in this setting and tried to identify factors affecting the probability of posttherapy remission.

Anthony Cousien, Sylvie Deuffic‐Burban, Yazdan Yazdanpanah – 11 January 2016

Harel Dahari, Scot J. Cotler, Jordan J. Feld – 11 January 2016

Jean Michel Mansuy, Pierre Gallian, Chloé Dimeglio, Karine Saune, Catherine Arnaud, Bertrand Pelletier, Pascal Morel, Dominique Legrand, Pierre Tiberghien, Jacques Izopet – 11 January 2016 – Most cases of hepatitis E viral (HEV) infection in developed countries are autochthonous. Nevertheless, the reported seroprevalence of HEV varies greatly depending on the geographical area and the performance of the immunoassay used.

Jean Michel Mansuy, Pierre Gallian, Chloé Dimeglio, Karine Saune, Catherine Arnaud, Bertrand Pelletier, Pascal Morel, Dominique Legrand, Pierre Tiberghien, Jacques Izopet – 11 January 2016 – Most cases of hepatitis E viral (HEV) infection in developed countries are autochthonous. Nevertheless, the reported seroprevalence of HEV varies greatly depending on the geographical area and the performance of the immunoassay used.

Shao‐Lai Zhou, Zhi‐Qiang Hu, Zheng‐Jun Zhou, Zhi Dai, Zheng Wang, Ya Cao, Jia Fan, Xiao‐Wu Huang, Jian Zhou – 11 January 2016 – MicroRNAs (miRNAs) play a critical role in regulation of tumor metastasis. However, the role of these molecules in hepatocellular carcinoma (HCC) has not been fully elucidated. In this study, we employed miRNA‐sequencing and identified 22 miRNAs involved in HCC metastasis. One of these, miR‐28‐5p, was down‐regulated in HCCs. This down‐regulation correlated with tumor metastasis, recurrence, and poor survival.

Salvatore Piano, Paolo Angeli – 11 January 2016

Francisco Javier Cubero – 11 January 2016

Leila Valanejad, Nikolai Timchenko – 11 January 2016