Cynthia Levy – 30 November 2015

Viniyendra Pamecha, Kishore Gurumoorthy Subramanya Bharathy, Senthil Kumar, Shridhar Vasantrao Sasturkar, Piyush Kumar Sinha – 26 November 2015 – Biliary complications after donor hepatectomy can result in significant morbidity. We herein present our experience of donor hepatectomy, highlighting surgical techniques that prevent complications. Data were reviewed from a prospectively maintained database of all donors who underwent hepatectomy from April 2011 to April 2015. Standard operative technique as described was followed in all patients.

Ezeldeen Abuelkasem, Michael A. Mazzeffi, Shu Yang Lu, Raymond M. Planinsic, Tetsuro Sakai, Kenichi A. Tanaka – 26 November 2015 – Prolonged prothrombin time (PT) and its ratio are routinely used for the assessment of candidates for liver transplantation (LT), but intraoperative coagulation management of transfusion is hindered by its long turnaround time.

Hideaki Uchiyama, Ken Shirabe, Koichi Kimura, Tomoharu Yoshizumi, Toru Ikegami, Norifumi Harimoto, Yoshihiko Maehara – 26 November 2015 – We conducted a retrospective investigation in order to clarify whether selecting the type of liver graft had an impact on outcomes of adult‐to‐adult living donor liver transplantation (AALDLT). Data from the medical records of the donors and the recipients of 321 consecutive cases of AALDLT performed between April 2004 and March 2014 were retrospectively analyzed.

Daniel Bushyhead, James N. Kirkpatrick, David Goldberg – 26 November 2015 – Despite advances in liver transplantation and preoperative risk stratification, there remains significant posttransplant morbidity and mortality from cardiovascular and renal disease. There are limited and conflicting data on the role of pretransplant echocardiography to predict these outcomes. The purpose of our study was to determine if pretransplant echocardiographic parameters were associated with posttransplant survival and the development of incident cardiovascular events and chronic kidney disease (CKD).

Gonzalo Crespo, Graciela Castro‐Narro, Ignacio García‐Juárez, Carlos Benítez, Pablo Ruiz, Lydia Sastre, Jordi Colmenero, Rosa Miquel, Alberto Sánchez‐Fueyo, Xavier Forns, Miquel Navasa – 26 November 2015 – Liver stiffness measurement (LSM) is a useful method to estimate liver fibrosis and portal hypertension. The inflammatory process that takes place in post–liver transplant acute cellular rejection (ACR) may also increase liver stiffness.

Hideaki Uchiyama, Ken Shirabe, Tomoharu Yoshizumi, Toru Ikegami, Norifumi Harimoto, Shinji Itoh, Koichi Kimura, Hirohisa Okabe, Yoshihiko Maehara – 26 November 2015

Nachiket Vartak, Amruta Damle‐Vartak, Beate Richter, Olaf Dirsch, Uta Dahmen, Seddik Hammad, Jan G. Hengstler – 26 November 2015 – Cholestasis is a common complication in liver diseases that triggers a proliferative response of the biliary tree. Bile duct ligation (BDL) is a frequently used model of cholestasis in rodents. To determine which changes occur in the three‐dimensional (3D) architecture of the interlobular bile duct during cholestasis, we used 3D confocal imaging, surface reconstructions, and automated image quantification covering a period up to 28 days after BDL.

25 November 2015

Benedetta Donati, Benedetta Maria Motta, Piero Pingitore, Marica Meroni, Alessandro Pietrelli, Anna Alisi, Salvatore Petta, Chao Xing, Paola Dongiovanni, Benedetta del Menico, Raffaela Rametta, Rosellina Margherita Mancina, Sara Badiali, Anna Ludovica Fracanzani, Antonio Craxì, Silvia Fargion, Valerio Nobili, Stefano Romeo, Luca Valenti – 25 November 2015 – The patatin‐like phosholipase domain‐containing 3 (PNPLA3) rs738409 polymorphism (I148M) is a major determinant of hepatic fat and predisposes to the full spectrum of liver damage in nonalcoholic fatty liver disease (NAFLD).