Retinoid regulation of antiviral innate immunity in hepatocytes
Noell E. Cho, Bo‐Ram Bang, Purnima Gurung, Meng Li, Dahn L. Clemens, T. Michael Underhill, Laura P. James, Jenifer R. Chase, Takeshi Saito – 5 December 2015 – Persistent infection of hepatitis C virus (HCV) is one of the leading causes of end‐stage liver disease (ESLD), such as decompensated cirrhosis and liver cancer. Of particular note, nearly half of HCV‐infected people in the United States are reported to be heavy drinkers. This particular group of patients is known to rapidly progress to the ESLD.