Local hypothyroidism favors the progression of preneoplastic lesions to hepatocellular carcinoma in rats

Carla Frau, Roberto Loi, Annalisa Petrelli, Andrea Perra, Silvia Menegon, Marta Anna Kowalik, Silvia Pinna, Vera Piera Leoni, Francesca Fornari, Laura Gramantieri, Giovanna Maria Ledda‐Columbano, Silvia Giordano, Amedeo Columbano – 25 August 2014 – Thyroid hormone receptors (TRs) are ligand‐dependent transcription factors that mediate most of the effects elicited by the thyroid hormone, 3,5,3′‐L‐triiodothyronine (T3).

Liver transplant patients have a risk of progression similar to that of sporadic patients with branch duct intraductal papillary mucinous neoplasms

Anne Marie Lennon, David Victor, Atif Zaheer, Mohammad Reza Ostovaneh, Jessica Jeh, Joanna K. Law, Neda Rezaee, Marco Dal Molin, Young Joon Ahn, Wenchuan Wu, Mouen A. Khashab, Mohit Girotra, Nita Ahuja, Martin A. Makary, Matthew J. Weiss, Kenzo Hirose, Michael Goggins, Ralph H. Hruban, Andrew Cameron, Christopher L. Wolfgang, Vikesh K. Singh, Ahmet Gurakar – 25 August 2014 – Intraductal papillary mucinous neoplasms (IPMNs) have malignant potential and can progress from low‐ to high‐grade dysplasia to invasive adenocarcinoma.

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