Should we use living donor grafts for patients with hepatocellular carcinoma? ethical considerations
Elizabeth A. Pomfret, J. Peter A. Lodge, Federico G. Villamil, Mark Siegler – 7 June 2011
Patients' expectations and success criteria for liver transplantation
James R. Rodrigue, Douglas W. Hanto, Michael P. Curry – 7 June 2011 – Patient‐reported outcomes are important to consider when the relative success of liver transplantation (LT) is being evaluated. Our primary objective was to examine the expectations for LT and the criteria for its success across 4 domains of functioning (pain, fatigue, emotional distress, and interference with daily activities) from the perspective of patients who were wait‐listed for LT.
Region‐specific challenges for minimizing endemic donor‐transmitted infections
Sherif Beniameen Mossad – 7 June 2011
2010 International consensus conference on liver transplantation for hepatocellular carcinoma: Texts of experts
Mickael Lesurtel, Pierre‐Alain Clavien – 7 June 2011
Social barriers to listing for adult liver transplantation: Their prevalence and association with program characteristics
Anna Flattau, Manhal Olaywi, Paul J. Gaglio, Paula Marcus, Paul Meissner, Emily B. L. Dorfman, John F. Reinus – 7 June 2011 – Social barriers to effective medical care are mandated to be routinely assessed as part of an evaluation for liver transplantation. This study explores how frequently liver transplant programs encounter these barriers in patients undergoing an evaluation and whether programs with higher proportions of Medicaid patients, historically disadvantaged minority patients, and rural patients encounter social barriers more frequently.
Cell line misidentification: The case of the Chang liver cell line
Qiang Gao, Xiao‐Ying Wang, Jian Zhou, Jia Fan – 7 June 2011
The reduction of SIRT1 in livers of old mice leads to impaired body homeostasis and to inhibition of liver proliferation
Jingling Jin, Polina Iakova, Yanjun Jiang, Estela E. Medrano, Nikolai A. Timchenko – 2 June 2011 – Age declines liver functions, leading to the development of age‐associated diseases. A member of the sirtuins family, SIRT1, is involved in the control of glucose homeostasis and fat metabolism. Because aging livers have alterations in glucose and fat metabolism, we examined a possible role of SIRT1 in these alterations. We found that aged livers have a reduced expression of SIRT1 and have lost proper control of the regulation of SIRT1 after partial hepatectomy (PH).
Hot topic in hepatitis C virus research: The type of immunosuppression does not matter
Marina Berenguer – 1 June 2011 – Key Points
Should the liver transplant criteria for hepatocellular carcinoma be different for deceased donation and living donation?
David Grant, Robert A. Fisher, Michael Abecassis, Geoffrey McCaughan, Linda Wright, Sheung‐Tat Fan – 1 June 2011
Liver allocation and distribution: Possible next steps
Kenneth Washburn, Elizabeth Pomfret, John Roberts – 1 June 2011 – Recent discussions about the distribution of cadaveric liver allografts for transplantation have raised many important issues. Over the past 2 years, a deliberative process including discussions, modeling, a request for information, a public forum, and a concept document has led to a greater focus on a possible path for reducing wait‐list mortality. Here we describe that process, our interpretation of the feedback and responses, and possible recommendations. Liver Transpl 17:1005–1012, 2011. © 2011 AASLD.