Optimization of the dosing regimen of mycophenolate mofetil in pediatric liver transplant recipients

Caroline Barau, Aurélie Barrail‐Tran, Bogdan Hemerziu, Dalila Habes, Anne‐Marie Taburet, Dominique Debray, Valérie Furlan – 21 June 2011 – Mycophenolate mofetil (MMF) is now commonly used in pediatric liver transplant recipients, but no clear recommendations about the dosing regimen have been made for this population. The aim of this study was to determine the MMF dosage required for pediatric liver transplant recipients to achieve an area under the plasma concentration–time curve from 0 to 12 hours (AUC0‐12) for mycophenolic acid (MPA) greater than 30 mg hour/L.

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