Elimination of hepatocellular carcinoma and acute hepatitis B in children 25 years after a hepatitis B newborn and catch‐up immunization program
Brian J. McMahon, Lisa R. Bulkow, Rosalyn J. Singleton, James Williams, Mary Snowball, Chriss Homan, Alan J. Parkinson – 26 May 2011 – Alaska Native people experience the highest rates of acute and chronic hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC) in the United States. We examined the effect of a universal newborn immunization with hepatitis B vaccine and mass population screening immunization program initiated in 1984 on rates of HBV and HCC in children 25 years later.