Ian Webzell, David Ball, James Bell, Roy A. Sherwood, Andrew Marsh, John G. O'Grady, Nigel D. Heaton – 8 July 2011 – Toxicological urinalysis is a highly sensitive and specific test that detects recent substance use. It has been established for substance misuse treatment but has not been routinely used at liver transplantation (LT) centers. Patients with a history of substance misuse are required to be abstinent from alcohol and illicit drugs before they are listed for LT.

Eric Levesque, Emir Hoti, Meriem Khalfallah, Chady Salloum, Luana Ricca, Eric Vibert, Daniel Azoulay – 8 July 2011 – Several donor and graft characteristics are associated with higher failure rates for deceased donor liver transplantation (LT). The influence of reversible cardiac arrest in the donor on these failure rates is unclear because of scarce and inconsistent data. The aim of this study was to determine whether reversible cardiac arrest in the donor could affect the early postoperative outcome of LT.

Seth A. Waits, Brandon M. Wojcik, Shijie Cai, Amit K. Mathur, Michael J. Englesbe – 8 July 2011 – The effect of occlusive portal vein thrombosis (PVT) on the mortality of pediatric liver transplant candidates and recipients is poorly defined. Using standard multivariate techniques, we studied the relationship between PVT and waiting‐list and posttransplant survival rates with data from the Scientific Registry of Transplant Recipients (September 2001 to December 2007). In all, 5087 liver transplant candidates and 3630 liver transplant recipients were evaluated during the period.

Beat Müllhaupt, Francois Durand, Tanja Roskams, Philipp Dutkowski, Markus Heim – 8 July 2011

Vishakha S. Bhave, Shirish Paranjpe, William C. Bowen, Shashikiran Donthamsetty, Aaron W. Bell, Jaspal S. Khillan, George K. Michalopoulos – 7 July 2011 – Reprogramming factors have been used to induce pluripotent stem cells as an alternative to somatic cell nuclear transfer technology in studies targeting disease models and regenerative medicine. The neuronal repressor RE‐1 silencing transcription factor (REST) maintains self‐renewal and pluripotency in mouse embryonic stem cells by maintaining the expression of Oct3/4, Nanog, and cMyc.

Jeong Min Lee, Franco Trevisani, Valerie Vilgrain, Christoph Wald – 7 July 2011

Abdirashid M. Shire, Lewis R. Roberts – 6 July 2011

Masanobu Tsuda, Yoko M. Ambrosini, Weici Zhang, Guo‐Xiang Yang, Yugo Ando, Guanghua Rong, Koichi Tsuneyama, Kosuke Sumida, Shinji Shimoda, Christopher L. Bowlus, Patrick S.C. Leung, Xiao‐Song He, Ross L. Coppel, Aftab A. Ansari, Zhe‐Xiong Lian, M. Eric Gershwin – 6 July 2011 – In primary biliary cirrhosis (PBC), patients develop a multilineage response to a highly restricted peptide of the E2 component of pyruvate dehydrogenase (PDC‐E2) involving autoantibody and autoreactive cluster of differentiation (CD)4+ and CD8+ T‐cell responses.

Wen Sun, Jin Ding, Kun Wu, Bei‐Fang Ning, Wen Wen, Han‐Yong Sun, Tao Han, Lei Huang, Li‐Wei Dong, Wen Yang, Xing Deng, Zhong Li, Meng‐Chao Wu, Gen‐Sheng Feng, Wei‐Fen Xie, Hong‐Yang Wang – 6 July 2011 – Gankyrin is a critical oncoprotein overexpressed in human hepatocellular carcinoma (HCC). However, the mechanism underlying gankyrin‐mediated hepatocarcinogenesis remains elusive. Herein, we provide evidence that gankyrin expression was progressively elevated in liver fibrosis, cirrhosis, and HCC.

Anna S. Lok – 6 July 2011