Stem cells or macrophages: Which contribute to bone marrow cell therapy for liver cirrhosis?
Tao Liu, Yingjie Wang, Chenting Wen, Shichang Zhang, Chunmei Zhang – 23 May 2011
MicroRNAs‐372/373 promote the expression of hepatitis B virus through the targeting of nuclear factor I/B
Hongyan Guo, Haiying Liu, Keith Mitchelson, Huiying Rao, Mingyong Luo, Lan Xie, Yimin Sun, Liang Zhang, Ying Lu, Ruyu Liu, Aihui Ren, Shuai Liu, Shaozhen Zhou, Jiye Zhu, Yuxiang Zhou, Ailong Huang, Lai Wei, Yong Guo, Jing Cheng – 23 May 2011 – MicroRNAs (miRNAs) play important roles in the posttranscriptional regulation of gene expression. Recent evidence has indicated the pathological relevance of miRNA dysregulation in hepatitis virus infection; however, the roles of microRNAs in the regulation of hepatitis B virus (HBV) expression are still largely unknown.
Saffron: A potential candidate for a novel anticancer drug against hepatocellular carcinoma
Amr Amin, Alaaeldin A. Hamza, Khuloud Bajbouj, S. Salman Ashraf, Sayel Daoud – 23 May 2011 – Saffron has been proposed as a promising candidate for cancer chemoprevention. The purpose of this investigation was to investigate the chemopreventive action and the possible mechanisms of saffron against diethylnitrosamine (DEN)‐induced liver cancer in rats. Administration of saffron at doses of 75, 150, and 300 mg/kg/day was started 2 weeks prior to the DEN injection and was continued for 22 weeks.
Absence of occult hepatitis C virus infection in patients under immunosupressive therapy for oncohematological diseases
Nicola Coppola, Mariantonietta Pisaturo, Salvatore Guastafierro, Gilda Tonziello, Antonello Sica, Caterina Sagnelli, Maria Giovanna Ferrara, Evangelista Sagnelli – 23 May 2011
Metabolic syndrome and liver cancer: Is excess iron the link?
Luca Mascitelli, Mark R. Goldstein – 23 May 2011
Autologous bone marrow mesenchymal stem cell transplantation in liver failure patients caused by hepatitis B: Short‐term and long‐term outcomes
Liang Peng, Dong‐ying Xie, Bing‐Liang Lin, Jing Liu, Hai‐peng Zhu, Chan Xie, Yu‐bao Zheng, Zhi‐liang Gao – 23 May 2011 – Our study aimed to investigate the short‐term efficacy and long‐term prognosis of liver failure patients caused by hepatitis B after a single transplantation with autologous marrow mesenchymal stem cells (MMSCs). A total of 527 inpatients with liver failure caused by hepatitis B were recruited and received the same medical treatments, among whom 53 patients underwent a single transplantation with autologous MMSCs.
Raised sympathetic activity and blood ammonia could increase sensitivity to infections in patients with cirrhosis and refractory ascites who are using beta‐blockers
Georgios N. Kalambokis, Epameinondas V. Tsianos – 23 May 2011
Liver transplantation for erythropoietic protoporphyria in Europe
Staffan Wahlin, Per Stal, Rene Adam, Vincent Karam, Robert Porte, Daniel Seehofer, Bridget K. Gunson, Jens Hillingsø, Jürgen L. Klempnauer, Jan Schmidt, Graeme Alexander, John O'Grady, Pierre‐Alain Clavien, Mauro Salizzoni, Andreas Paul, Keith Rolles, Bo‐Göran Ericzon, Pauline Harper, for the European Liver and Intestine Transplant Association – 20 May 2011 – Liver transplantation is an established lifesaving treatment for patients with severe protoporphyric liver disease, but disease recurrence in the graft occurs for the majority of recipients.
Ambivalence in living liver donors
Mary Ann Simpson, Julia Kendrick, Jennifer E. Verbesey, Denise S. Morin, Mary Amanda Dew, Agnes Trabucco, James J. Pomposelli, Elizabeth A. Pomfret – 20 May 2011 – All right hepatic lobe (RHL) donors in our program are asked to participate in a longitudinal quality‐of‐life study that begins at their evaluation and continues throughout the first postdonation year. Here we report the characteristics of donor candidates who completed the donation process despite ambivalence. In all, 183 RHL candidates consented, and 133 became donors.