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Hitendra Garg, Shiv Kumar Sarin, Manoj Kumar, Vishal Garg, Barjesh Chander Sharma, Ashish Kumar – 23 May 2011

MicroRNAs‐372/373 promote the expression of hepatitis B virus through the targeting of nuclear factor I/B

Hongyan Guo, Haiying Liu, Keith Mitchelson, Huiying Rao, Mingyong Luo, Lan Xie, Yimin Sun, Liang Zhang, Ying Lu, Ruyu Liu, Aihui Ren, Shuai Liu, Shaozhen Zhou, Jiye Zhu, Yuxiang Zhou, Ailong Huang, Lai Wei, Yong Guo, Jing Cheng – 23 May 2011 – MicroRNAs (miRNAs) play important roles in the posttranscriptional regulation of gene expression. Recent evidence has indicated the pathological relevance of miRNA dysregulation in hepatitis virus infection; however, the roles of microRNAs in the regulation of hepatitis B virus (HBV) expression are still largely unknown.

Saffron: A potential candidate for a novel anticancer drug against hepatocellular carcinoma

Amr Amin, Alaaeldin A. Hamza, Khuloud Bajbouj, S. Salman Ashraf, Sayel Daoud – 23 May 2011 – Saffron has been proposed as a promising candidate for cancer chemoprevention. The purpose of this investigation was to investigate the chemopreventive action and the possible mechanisms of saffron against diethylnitrosamine (DEN)‐induced liver cancer in rats. Administration of saffron at doses of 75, 150, and 300 mg/kg/day was started 2 weeks prior to the DEN injection and was continued for 22 weeks.

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