“Real‐Life” comparison of pegylated‐interferon 2a versus 2b combination therapy of chronic hepatitis C virus
Julian Schulze zur Wiesch, Neele Pudelski, Lena Hoepner, Michael Supplieth, Peter Buggisch, Ansgar W. Lohse, Stefan Lüth – 10 January 2011
Dietary supplementation with methyl donor groups could prevent nonalcoholic fatty liver
Pául Cordero, Javier Campion, Fermín I. Milagro, J. Alfredo Martínez – 10 January 2011
Noncirrhotic presinusoidal portal hypertension is common in cystic fibrosis–associated liver disease
Peter Witters, Louis Libbrecht, Tania Roskams, Kris De Boeck, Lieven Dupont, Marijke Proesmans, François Vermeulen, Birgitta Strandvik, Anders Lindblad, Xavier Stéphenne, Etienne Sokal, Serge Gosseye, Sam Heye, Geert Maleux, Raymond Aerts, Diethard Monbaliu, Jacques Pirenne, Ilse Hoffman, Frederik Nevens, David Cassiman – 10 January 2011
Insulin sensitizers in nonalcoholic steatohepatitis
Stephen A. Harrison, Steven Schenker, Kenneth Cusi – 10 January 2011
Is hydrophobia necessary for the hepatologist prescribing nonselective beta‐blockers in cirrhosis?
Marco Senzolo, Elena Nadal, Evangelos Cholongitas, Andrew K. Burroughs – 10 January 2011
Explanted liver inflammatory grade predicts fibrosis progression in hepatitis C recurrence
Marwan Ghabril, Rolland C. Dickson, Murli Krishna, Victor Machicao, Jaime Aranda‐Michel, Hugo Bonatti, Justin H. Nguyen – 10 January 2011 – Factors present prior to liver transplantation (LT) that predict fibrosis progression in recurrent hepatitis C infection (HCV) after LT would be important to identify. This study sought to determine if histologic grade of HCV in the explant predicts fibrosis progression in recurrent HCV.
Outcomes in children who underwent transplantation for autoimmune hepatitis
Steven R. Martin, Fernando Alvarez, Ravinder Anand, Changhong Song, Wanrong Yin – 6 January 2011 – The outcomes of 113 children with autoimmune hepatitis (AIH), registered with Studies of Pediatric Liver Transplantation and who underwent transplantation between 1995 and 2006, were compared with those who underwent transplantation for other diagnoses (non‐AIH). A total of 4.9% of liver transplants were for AIH; 81% of these patients had AIH type 1 and most underwent transplantation for complications of chronic disease (60%), the majority in females (72%).
The GRACILE mutation introduced into Bcs1l causes postnatal complex III deficiency: A viable mouse model for mitochondrial hepatopathy
Per Levéen, Heike Kotarsky, Matthias Mörgelin, Riitta Karikoski, Eskil Elmér, Vineta Fellman – 28 December 2010 – Mitochondrial dysfunction is an important cause for neonatal liver disease. Disruption of genes encoding oxidative phosphorylation (OXPHOS) components usually causes embryonic lethality, and thus few disease models are available. We developed a mouse model for GRACILE syndrome, a neonatal mitochondrial disease with liver and kidney involvement, caused by a homozygous BCS1L mutation (232A>G).
Massive hepatic echinococcosis
Seth Sweetser, Conor G. Loftus – 22 December 2010
Early predictors of corticosteroid treatment failure in icteric presentations of autoimmune hepatitis
Andrew D. Yeoman, Rachel H. Westbrook, Yoh Zen, Paola Maninchedda, Bernard C. Portmann, John Devlin, John G. O'Grady, Phillip M. Harrison, Michael A. Heneghan – 22 December 2010 – Autoimmune hepatitis (AIH) typically responds to treatment in 90% of patients. Early prediction of treatment outcome would be advantageous in clinical practice. We evaluated whether parameters at initiation of therapy or changes in these parameters at day 3 and day 7 following corticosteroid initiation predicted treatment failure.