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Elsa Solà, Sabela Lens, Mónica Guevara, Pere Ginès – 11 January 2011
Excess mortality in patients with advanced chronic hepatitis C treated with long‐term peginterferon
Adrian M. Di Bisceglie, Anne M. Stoddard, Jules L. Dienstag, Mitchell L. Shiffman, Leonard B. Seeff, Herbert L. Bonkovsky, Chihiro Morishima, Elizabeth C. Wright, Kristin K. Snow, William M. Lee, Robert J. Fontana, Timothy R. Morgan, Marc G. Ghany, for the HALT‐C Trial Group – 11 January 2011 – Chronic hepatitis C virus infection can cause chronic liver disease, cirrhosis and liver cancer.
The wide spectrum of hepatic iron overload
Melania Manco, Anna Alisi, Antonella Mosca, Valerio Nobili – 11 January 2011
Autoimmune hepatitis and antigen‐specific T regulatory cells: When can we send in the regulators?
John M. Vierling – 11 January 2011
Dietary supplementation with methyl donor groups could prevent nonalcoholic fatty liver
Pául Cordero, Javier Campion, Fermín I. Milagro, J. Alfredo Martínez – 10 January 2011
“Real‐Life” comparison of pegylated‐interferon 2a versus 2b combination therapy of chronic hepatitis C virus
Julian Schulze zur Wiesch, Neele Pudelski, Lena Hoepner, Michael Supplieth, Peter Buggisch, Ansgar W. Lohse, Stefan Lüth – 10 January 2011
Hepatitis B virus infection and risk of intrahepatic cholangiocarcinoma and non‐Hodgkin lymphoma: A cohort study of parous women in Taiwan
Chyng‐Wen Fwu, Yin‐Chu Chien, San‐Lin You, Kenrad E. Nelson, Gregory D. Kirk, Hsu‐Sung Kuo, Manning Feinleib, Chien‐Jen Chen – 10 January 2011 – Few studies have evaluated the risk of cancers other than hepatocellular carcinoma associated with hepatitis B virus (HBV) infection. This study aimed to estimate incidence rates of intrahepatic cholangiocarcinoma (ICC) and non‐Hodgkin lymphoma (NHL) and its major subtypes in a nationwide cohort of parous women and to assess their associations with chronic HBV infection.
Occludin is regulated by epidermal growth factor receptor activation in brain endothelial cells and brains of mice with acute liver failure
Feng Chen, Tomohide Hori, Norifumi Ohashi, Ann‐Marie Baine, Christopher B. Eckman, Justin H. Nguyen – 10 January 2011 – Mechanisms of brain edema in acute liver failure (ALF) are not completely understood. We recently demonstrated that matrix metalloproteinase 9 (MMP‐9) induces significant alterations to occludin in brain endothelial cells in vitro and in brains of mice with experimental ALF (Hepatology 2009;50:1914).
Hepatic stellate cells regulate immune response by way of induction of myeloid suppressor cells in mice
Hong‐Shiue Chou, Ching‐Chuan Hsieh, Horng‐Ren Yang, Lianfu Wang, Yusuke Arakawa, Kathleen Brown, Qingyu Wu, Feng Lin, Marion Peters, John J. Fung, Lina Lu, Shiguang Qian – 10 January 2011 – Although organ transplants have been applied for decades, outcomes of somatic cell transplants remain disappointing, presumably due to lack of appropriate supporting stromal cells.
Proteins ZNF198 and SUZ12 are down‐regulated in hepatitis B virus (HBV) X protein‐mediated hepatocyte transformation and in HBV replication
Wen‐Horng Wang, Leo L. Studach, Ourania M. Andrisani – 10 January 2011 – Chronic hepatitis B virus (HBV) infection is a major etiologic factor in hepatocellular carcinoma (HCC) pathogenesis, involving effects of chronic liver inflammation and of the weakly oncogenic HBV X protein (pX). pX‐mediated hepatocyte transformation requires Polo‐like kinase1 (Plk1) activity, but the mechanism is not fully understood.