Patients with non–[18F]fludeoxyglucose‐avid advanced hepatocellular carcinoma on clinical staging may achieve long‐term recurrence‐free survival after liver transplantation

Arno Kornberg, Bernadett Küpper, Andrea Tannapfel, Peter Büchler, Babette Krause, Ulrike Witt, Dietmar Gottschild, Helmut Friess – 17 August 2011 – There is increasing evidence that a relevant number of patients with hepatocellular carcinoma (HCC) exceeding the Milan criteria may benefit from liver transplantation (LT). We retrospectively analyzed the prognostic significance of [18F]fludeoxyglucose ([18F]FDG) positron emission tomography (PET) for identifying appropriate LT candidates with advanced HCC on clinical staging. Between 1995 and 2008, 111 patients with HCC were listed for LT.

Computed tomography liver volumetry using 3‐dimensional image data in living donor liver transplantation: Effects of the slice thickness on the volume calculation

Masatoshi Hori, Kenji Suzuki, Mark L. Epstein, Richard L. Baron – 17 August 2011 – The purpose of this study was to evaluate the relationship between the slice thickness and the calculated volume in computed tomography (CT) liver volumetry through the comparison of the results from images [including 3‐dimensional (3D) images] with various slice thicknesses. Twenty potential adult liver donors (12 men and 8 women) with a mean age of 39 years (range = 24‐64 years) underwent CT with a 64‐section multidetector row CT scanner after the intravenous injection of a contrast material.

Living donor hepatectomy: The importance of the residual liver volume

Trevor W. Reichman, Charbel Sandroussi, Solomon M. Azouz, Lesley Adcock, Mark S. Cattral, Ian D. McGilvray, Paul D. Greig, Anand Ghanekar, Markus Selzner, Gary Levy, David R. Grant – 17 August 2011 – Living liver donation is a successful treatment for patients with end‐stage liver disease. Most adults are provided with a right lobe graft to ensure a generous recipient liver volume. Some centers are re‐exploring the use of smaller left lobe grafts to potentially reduce the donor risk.

Carbon monoxide induces hypothermia tolerance in Kupffer cells and attenuates liver ischemia/reperfusion injury in rats

Lung‐Yi Lee, Takashi Kaizu, Hideyoshi Toyokawa, Matthew Zhang, Mark Ross, Donna B. Stolz, Chao Huang, Chandrashekhar Gandhi, David A. Geller, Noriko Murase – 17 August 2011 – Ischemia/reperfusion (I/R) injury in liver grafts, which is initiated by cold preservation and is augmented by reperfusion, is a major problem that complicates graft quality, posttransplant patient care, and outcomes of liver transplantation (LT). Kupffer cells (KCs) play important roles in I/R injury; however, little is known about their changes during cold preservation.

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