Comment on a systematic review of randomized trials of peginterferon alpha‐2a versus peginterferon alpha‐2b in chronic hepatitis C
Ashwani K. Singal, Sarat C. Jampana, Bhupinderjit S. Anand – 10 January 2011
Inflammation does not always kill hepatocytes during liver damage
Honglei Weng, Hai Li, Steven Dooley – 10 January 2011
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Lionel Piroth, Christine Larsen, Elisabeth Delarocque‐Astagneau, Stanislas Pol – 10 January 2011
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Milan J. Sonneveld, Vincent Rijckborst, Harry L.A. Janssen – 10 January 2011
In vitro steroid resistance correlates with outcome in severe alcoholic hepatitis
A.J. di Mambro, R. Parker, A. McCune, F. Gordon, C.M. Dayan, P. Collins – 10 January 2011 – Steroids improve the outcome in alcoholic hepatitis (AH), but up to 40% of patients fail to respond adequately. Interleukin‐2 (IL‐2) exacerbates steroid resistance in vitro. We performed a prospective study to determine if intrinsic steroid sensitivity correlates with response to steroids in individuals with severe AH and if IL‐2 receptor blockade can reverse this. Peripheral blood mononuclear cells (PBMCs) were isolated from 20 patients with AH and a Maddrey's score >32.
Risk factors of lung, head and neck, esophageal, and kidney and urinary tract carcinomas after liver transplantation: The effect of smoking withdrawal
J. Ignacio Herrero, Fernando Pardo, Delia D'Avola, Félix Alegre, Fernando Rotellar, Mercedes Iñarrairaegui, Pablo Martí, Bruno Sangro, Jorge Quiroga – 10 January 2011 – Liver transplant recipients have an increased risk of malignancy. Smoking is related to some of the most frequent causes of posttransplant malignancy. The incidence and risk factors for the development of neoplasia related to smoking (head and neck, lung, esophageal, and kidney and urinary tract carcinomas) were studied in 339 liver transplant recipients.
Explanted liver inflammatory grade predicts fibrosis progression in hepatitis C recurrence
Marwan Ghabril, Rolland C. Dickson, Murli Krishna, Victor Machicao, Jaime Aranda‐Michel, Hugo Bonatti, Justin H. Nguyen – 10 January 2011 – Factors present prior to liver transplantation (LT) that predict fibrosis progression in recurrent hepatitis C infection (HCV) after LT would be important to identify. This study sought to determine if histologic grade of HCV in the explant predicts fibrosis progression in recurrent HCV.
Is hydrophobia necessary for the hepatologist prescribing nonselective beta‐blockers in cirrhosis?
Marco Senzolo, Elena Nadal, Evangelos Cholongitas, Andrew K. Burroughs – 10 January 2011
Insulin sensitizers in nonalcoholic steatohepatitis
Stephen A. Harrison, Steven Schenker, Kenneth Cusi – 10 January 2011
Noncirrhotic presinusoidal portal hypertension is common in cystic fibrosis–associated liver disease
Peter Witters, Louis Libbrecht, Tania Roskams, Kris De Boeck, Lieven Dupont, Marijke Proesmans, François Vermeulen, Birgitta Strandvik, Anders Lindblad, Xavier Stéphenne, Etienne Sokal, Serge Gosseye, Sam Heye, Geert Maleux, Raymond Aerts, Diethard Monbaliu, Jacques Pirenne, Ilse Hoffman, Frederik Nevens, David Cassiman – 10 January 2011