Reply: Comments on AASLD practice guidelines for alcoholic liver disease
Arthur McCullough, Srinivasan Dasarathy, Robert O'Shea – 22 April 2010
Reply: Is oil red‐O staining and digital image analysis the gold standard for quantifying steatosis in the liver?
Manal F. Abdelmalek – 22 April 2010
Alcoholic liver disease: The buzz may be gone, but the hangover remains
Vijay H. Shah – 22 April 2010
Dissociation between liver inflammation and hepatocellular damage induced by carbon tetrachloride in myeloid cell–specific signal transducer and activator of transcription 3 gene knockout mice
Norio Horiguchi, Fouad Lafdil, Andrew M. Miller, Ogyi Park, Hua Wang, Mohanraj Rajesh, Partha Mukhopadhyay, Xin Yuan Fu, Pal Pacher, Bin Gao – 22 April 2010 – Liver injury is associated with inflammation, which is generally believed to accelerate the progression of liver diseases; however, clinical data show that inflammation does not always correlate with hepatocelluar damage in some patients.
Clearing the smoke in chronic liver diseases
Claudia O. Zein – 22 April 2010
Generation of endoderm‐derived human induced pluripotent stem cells from primary hepatocytes
Hua Liu, Zhaohui Ye, Yonghak Kim, Saul Sharkis, Yoon‐Young Jang – 22 April 2010 – Recent advances in induced pluripotent stem (iPS) cell research have significantly changed our perspective on regenerative medicine. Patient‐specific iPS cells have been derived not only for disease modeling but also as sources for cell replacement therapy. However, there have been insufficient data to prove that iPS cells are functionally equivalent to human embryonic stem (hES) cells or are safer than hES cells.
Hepatitis C virus genotype 2/3 patients who can receive an abbreviated course of peginterferon/ribavirin: The important role of initial ribavirin doses
Chia‐Yen Dai, Chung‐Feng Huang, Jee‐Fu Huang, Wan‐Long Chuang, Ming‐Lung Yu – 22 April 2010
Hepatic glycosphingolipid deficiency and liver function in mice
Richard Jennemann, Ulrike Rothermel, Shijun Wang, Roger Sandhoff, Sylvia Kaden, Ruud Out, Theo J. van Berkel, Johannes M. Aerts, Karen Ghauharali, Carsten Sticht, Hermann‐Josef Gröne – 22 April 2010 – Recent studies have reported that glycosphingolipids (GSLs) might be involved in obesity‐induced insulin resistance. Those reports suggested that inhibition of GSL biosynthesis in animals ameliorated insulin resistance accompanied by improved glycemic control and decreased liver steatosis in obese mice. In addition, pharmacologic GSL depletion altered hepatic secretory function.
Clearance of hepatitis B surface antigen and risk of hepatocellular carcinoma in a cohort chronically infected with hepatitis B virus
Josephine Simonetti, Lisa Bulkow, Brian J. McMahon, Chriss Homan, Mary Snowball, Susan Negus, James Williams, Stephen E. Livingston – 22 April 2010 – Some individuals who are chronically infected with hepatitis B virus (HBV) eventually lose hepatitis B surface antigen (HBsAg). Hepatocellular carcinoma (HCC) has been demonstrated to occur in a few patients after loss of HBsAg. Neither factors associated with loss of HBsAg nor the incidence of HCC thereafter have been clearly elucidated.