Treatment of Small‐For‐Size Syndrome

James D. Perkins – 26 March 2008 – The portal hyperperfusion, or small‐for‐size syndrome (SFSS), is a widely recognized clinical complication that may occur after segmental liver transplantation. Several surgical strategies have been proposed to reduce portal blood inflow and portal pressure after partial liver transplantation. In particular, splenic artery ligation and splenectomy have been used without a firm hemodynamic basis for these procedures.

Health‐related quality of life and family function following pediatric liver transplantation

Estella M. Alonso, Katie Neighbors, Franca B. Barton, Sue V. McDiarmid, Stephen P. Dunn, George V. Mazariegos, Jeanne M. Landgraf, John C. Bucuvalas – 26 March 2008 – This multicenter study compared health‐related quality of life (HRQOL) and family function of pediatric liver transplant recipients to those of healthy children to determine if this population differed from a healthy population and to distinguish which pretransplant and posttransplant factors impact HRQOL and family function.

Chronic hepatitis E virus infection in liver transplant recipients

Elizabeth B. Haagsma, Arie P. van den Berg, Robert J. Porte, Cornelis A. Benne, Harry Vennema, Johan H. J. Reimerink, Marion P. G. Koopmans – 26 March 2008 – Hepatitis E virus (HEV) infection is known to run a self‐limiting course. Sporadic cases of acute hepatitis due to infection with HEV genotype 3, present in pig populations, are increasingly recognized. Zoonotic transmission seems infrequent. The entity of unexplained chronic hepatitis after liver transplantation has been recognized. Detection of HEV in 2 liver transplant recipients triggered a review of these cases.

Steroid avoidance in liver transplantation: Meta‐analysis and meta‐regression of randomized trials

Dorry L. Segev, Stephen M. Sozio, Eun Ji Shin, Susanna M. Nazarian, Hari Nathan, Paul J. Thuluvath, Robert A. Montgomery, Andrew M. Cameron, Warren R. Maley – 26 March 2008 – Steroid use after liver transplantation (LT) has been associated with diabetes, hypertension, hyperlipidemia, obesity, and hepatitis C (HCV) recurrence. We performed meta‐analysis and meta‐regression of 30 publications representing 19 randomized trials that compared steroid‐free with steroid‐based immunosuppression (IS). There were no differences in death, graft loss, and infection.

Metabolic liver disease in children

Keli Hansen, Simon Horslen – 26 March 2008 – The aim of this article is to provide essential information for hepatologists, who primarily care for adults, regarding liver‐based inborn errors of metabolism with particular reference to those that may be treatable with liver transplantation and to provide adequate references for more in‐depth study should one of these disease states be encountered. Liver Transpl 14:391–411, 2008. © 2008 AASLD.

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