Mariapia Vairetti, Andrea Ferrigno, Vittoria Rizzo, Eleonora Boncompagni, Amedeo Carraro, Enrico Gringeri, Gloria Milanesi, Sergio Barni, Isabel Freitas, Umberto Cillo – 26 March 2008 – This study compares the effects of machine perfusion (MP) at different temperatures with simple cold storage. In addition, the role of Ca2+ levels in the MP medium was evaluated. For MP, rat livers were perfused for 6 hours with Krebs‐Henseleit (KH) solution (with 1.25 or 2.5 mM CaCl2) at 4°C, 10°C, 20°C, 25°C, 30°C, or 37°C.

Lorenzo Norberto, Andrew Burroughs, Lino Polese – 26 March 2008

Maria Elena Fortes, Cláudio Augusto Marroni, Pedro Luis Coser, Carlos Abaeté de los Santos – 26 March 2008 – The aim of the study was to disclose a possible association of hearing defects with the use of either cyclosporin (CyA) or tacrolimus (FK‐506) in patients undergoing liver transplantation (LT). Pure‐tone audiometry (PTA) was performed in the same 42 patients before and after LT. Audiometric frequencies recorded ranged from 250 to 8000 Hz. Patients were divided into 2 groups according to the use of CyA (n = 18) or FK‐506 (n = 24).

Ayako Tsuchiya, Masahide Yazaki, Fuyuki Kametani, Yo‐ichi Takei, Shu‐ichi Ikeda – 26 March 2008 – To elucidate whether the amount of tissue‐deposited amyloid in familial amyloid polyneuropathy (FAP) patients decreases or increases over the long‐term course after liver transplantation (LT), we examined changes in histopathological and biochemical characteristics of abdominal fat amyloid in the transplanted patients with a postoperative history of more than 10 years.

Vicky Lee Ng, Anthony R. Otley – 26 March 2008

Chun‐Tao Wai, Kang‐Hoe Lee, Kai‐Chah Tan – 26 March 2008

Yaakov Nahmias, Martin L. Yarmush, Raymond T. Chung – 26 March 2008

Michael Adler, Filip De Pauw, Pierre Vereerstraeten, Agnese Fancello, Jan Lerut, Peter Starkel, Hans Van Vlierberghe, Roberto Troisi, Vincent Donckier, Olivier Detry, Jean Delwaide, Peter Michielsen, Thierry Chapelle, Jacques Pirenne, Frederik Nevens – 26 March 2008 – Although hepatocellular carcinoma (HCC) has become a recognized indication for liver transplantation, the rules governing priority and access to the waiting list are not well defined.

Sahar Hassan‐Khabbar, Charles‐Henry Cottart, Dominique Wendum, Françoise Vibert, Jean‐Pierre Clot, Jean‐François Savouret, Marc Conti, Valérie Nivet‐Antoine – 26 March 2008 – Liver ischemia‐reperfusion (I/R) injury occurs in many clinical conditions, including liver surgery and transplantation. Oxygen free radicals generated during I/R reduce endogenous antioxidant systems and contribute to hepatic injury. trans‐Resveratrol (trans‐3,5,4′‐trihydroxystilbene) is reported to have antioxidant properties. We investigated the effect of trans‐resveratrol on liver injury induced by I/R.

Marcela Castillo‐Rama, Maria Jose Castro, Ivan Bernardo, Juan Carlos Meneu‐Diaz, Almudena Moreno Elola‐Olaso, Sara M. Calleja‐Antolin, Eva Romo, Pablo Morales, Enrique Moreno, Estela Paz‐Artal – 26 March 2008 – The significance of human leukocyte antigen (HLA) compatibility and preformed antibodies in liver transplantation remains unclear. The objectives of this study were to evaluate, in a single‐center cohort comprising 896 liver transplants, whether the degree of donor‐recipient compatibility and preformed antibodies modified graft survival.