Richard B. Freeman – 29 July 2009

Kevin T. Shiley, Leanne B. Gasink, Todd D. Barton, Patrice Pfeiffenberger, Kim M. Olthoff, Emily A. Blumberg – 29 July 2009 – Optimal measures for the prevention of cytomegalovirus (CMV) in high‐risk orthotopic liver transplant (OLT) patients are unknown. The charts of high‐risk OLT recipients with 12 months of follow‐up who were transplanted over a 44‐month period were reviewed. The incidence of CMV disease in CMV‐seropositive donor/CMV‐seronegative recipient patients receiving valganciclovir or ganciclovir prophylaxis was compared.

Yoichiro Uchida, Maria Cecilia S. Freitas, Danyun Zhao, Ronald W. Busuttil, Jerzy W. Kupiec‐Weglinski – 29 July 2009 – Neutrophils are considered crucial effector cells in the pathophysiology of organ ischemia/reperfusion injury (IRI). Although neutrophil elastase (NE) accounts for a substantial portion of the neutrophil activity, the function of NE in liver IRI remains unclear. This study focuses on the role of NE in the mechanism of liver IRI.

Holenarasipur R. Vikram, Shimon Kusne – 29 July 2009

James D. Perkins – 29 July 2009

Paul J. Thuluvath – 29 July 2009

Gregory A. Eschenauer, Simon W. Lam, Peggy L. Carver – 29 July 2009 – Although the overall incidence of fungal infections in liver transplant recipients has declined, these infections still contribute significantly to the morbidity and mortality of patients with risk factors for infection. Although antifungal prophylaxis has been widely studied and practiced, no consensus exists on which patients should receive prophylaxis, with which agent, and for what duration.

Junfang Ji, Taro Yamashita, Anuradha Budhu, Marshonna Forgues, Hu‐Liang Jia, Cuiling Li, Chuxia Deng, Elaine Wauthier, Lola M. Reid, Qing‐Hai Ye, Lun‐Xiu Qin, Wen Yang, Hong‐Yang Wang, Zhao‐You Tang, Carlo M. Croce, Xin Wei Wang – 29 July 2009 – MicroRNAs (miRNAs) are endogenous small noncoding RNAs that regulate gene expression with functional links to tumorigenesis. Hepatocellular carcinoma (HCC) is the most common type of liver cancer, and it is heterogeneous in clinical outcomes and biological activities.

Paulette Bioulac‐Sage, Hervé Laumonier, Gabrielle Couchy, Brigitte Le Bail, Antonio Sa Cunha, Anne Rullier, Christophe Laurent, Jean‐Frédéric Blanc, Gaelle Cubel, Hervé Trillaud, Jessica Zucman‐Rossi, Charles Balabaud, Jean Saric – 29 July 2009 – We took advantage of the reported genotype/phenotype classification to analyze our surgical series of hepatocellular adenoma (HCA). The series without specific known etiologies included 128 cases (116 women). The number of nodules varies from single, <5, and ≥5 in 78, 38, and 12 cases, respectively. The resection was complete in 95 cases.

Bibiana Escobar, Pilar Taura, Nelson Barreneche, Joan Beltran, Jaume Balust, Graciela Martinez‐Palli, Elizabeth Zavala, Angels Escorsell, Juan Carlos Garcia‐Valdecasas – 29 July 2009 – Familial amyloidotic polyneuropathy (FAP) patients present adrenergic cardiac input blockade secondary to amyloid deposits and sympathetic neuropathy. Consequently, their capacity to compensate for hemodynamic changes is limited. To avoid hemodynamic disturbances in sequential liver transplants, a standard procedure with venovenous bypass or inferior vena cava preservation is contemplated.