Metastatic tumor antigen 1 is closely associated with frequent postoperative recurrence and poor survival in patients with hepatocellular carcinoma

Soo Hyung Ryu, Young‐Hwa Chung, Hyunseung Lee, Jeong A. Kim, Hyun Deok Shin, Hyun Joo Min, Dong Dae Seo, Myoung Kuk Jang, Eunsil Yu, Kyu‐Won Kim – 27 February 2008 – Metastatic tumor antigen 1 (MTA1) is known to play a role in angiogenic processes as a stabilizer of hypoxia‐inducible factor 1‐α (HIF1‐α). In this study, we examined whether overexpression of MTA1 affects the recurrence of hepatocellular carcinoma (HCC) after surgical resection and the survival of the patients. A total of 506 HCC patients who underwent hepatic resection were included in the study.

Reply:

Dominique Thabut, Khalid Tazi, Dominique Bonnefont‐Rousselot, Richard Moreau, Didier Lebrec – 27 February 2008

Isolation and characterization of a novel population of progenitor cells from unmanipulated rat liver

M. Behnan Sahin, Robert E. Schwartz, Shannon M. Buckley, Yves Heremans, Lucas Chase, Wei‐Shou Hu, Catherine M. Verfaillie – 27 February 2008 – Widespread use of liver transplantation in the treatment of hepatic diseases is restricted by the limited availability of donated organs. One potential solution to this problem would be isolation and propagation of liver progenitor cells or stem cells. Here, we report on the isolation of a novel progenitor cell population from unmanipulated (that is, no prior exposure to chemicals and no injury) adult rat liver.

Subscribe to