M. Behnan Sahin, Robert E. Schwartz, Shannon M. Buckley, Yves Heremans, Lucas Chase, Wei‐Shou Hu, Catherine M. Verfaillie – 27 February 2008 – Widespread use of liver transplantation in the treatment of hepatic diseases is restricted by the limited availability of donated organs. One potential solution to this problem would be isolation and propagation of liver progenitor cells or stem cells. Here, we report on the isolation of a novel progenitor cell population from unmanipulated (that is, no prior exposure to chemicals and no injury) adult rat liver.

Zhiping Li – 27 February 2008

Dominique Thabut, Khalid Tazi, Dominique Bonnefont‐Rousselot, Richard Moreau, Didier Lebrec – 27 February 2008

Thomas Johnston, Hoonbae Jeon, Roberto Gedaly, Dinesh Ranjan – 27 February 2008

Soo Hyung Ryu, Young‐Hwa Chung, Hyunseung Lee, Jeong A. Kim, Hyun Deok Shin, Hyun Joo Min, Dong Dae Seo, Myoung Kuk Jang, Eunsil Yu, Kyu‐Won Kim – 27 February 2008 – Metastatic tumor antigen 1 (MTA1) is known to play a role in angiogenic processes as a stabilizer of hypoxia‐inducible factor 1‐α (HIF1‐α). In this study, we examined whether overexpression of MTA1 affects the recurrence of hepatocellular carcinoma (HCC) after surgical resection and the survival of the patients. A total of 506 HCC patients who underwent hepatic resection were included in the study.

William M. Lee – 27 February 2008

Andre M. De Wolf, Shushma Aggarwal – 27 February 2008

Kevin P. Charpentier, Arun Mavanur – 27 February 2008 – Guidelines are in place regarding who is a candidate for liver transplantation. Once a potential candidate is listed, there are no uniform guidelines indicating when he should be removed from the list because of a change in clinical status. A survey with 14 scenarios was sent to the medical and surgical directors of all liver transplant programs in the United States. In each scenario, clinical information was provided about a patient active on the transplant wait list.

Richard S. Mangus, Jonathon A. Fridell, Rodrigo M. Vianna, Martin A. Milgrom, Paul Chestovich, Ray K. Chihara, A. Joseph Tector – 27 February 2008 – Liver, pancreas, and kidney allografts preserved in histidine‐tryptophan‐ketoglutarate (HTK) and University of Wisconsin (UW) solutions have similar clinical outcomes. This study compares HTK and UW in a large number of standard criteria donor (SCD) and extended criteria donor (ECD) livers at a single center over 5 years.

Amy A. Dan, Jillian B. Kallman, Ragini Srivastava, Zahra Younoszai, Amy Kim, Zobair M. Younossi – 27 February 2008 – Assessment of health‐related quality of life (HRQL) and health utilities have become important aspects of clinical research. Patient‐derived utility adjustments are frequently used in economic analysis. Although HRQL has been frequently studied among patients with liver disease, extensive data on the health utilities of patients with liver disease are not available. Recently, SF‐6D has been developed to obtain utility scores from the widely used Short Form 36 questionnaire.