Bo Shen, Jun Yu, Shiyan Wang, Eagle S.H. Chu, V.W.S. Wong, Xin Zhou, Ge Lin, Joseph J.Y. Sung, Henry L.Y. Chan – 26 January 2008 – Hepatic oxidative stress plays a critical role in metabolic forms of steatohepatitis. Phyllanthus urinaria, an herbal medicine, has been reported to have potential antioxidant properties. We tested the effects of P. urinaria on nutritional steatohepatitis both in vitro and in vivo. Immortalized normal hepatocytes (AML‐12) or primary hepatocytes were exposed to control, the methionine‐and‐choline‐deficient (MCD) culture medium, in the presence or absence of P.

Luca Fabris, Massimiliano Cadamuro, Louis Libbrecht, Peggy Raynaud, Carlo Spirlì, Romina Fiorotto, Lajos Okolicsanyi, Frederic Lemaigre, Mario Strazzabosco, Tania Roskams – 26 January 2008 – Intrahepatic bile ducts maintain a close anatomical relationship with hepatic arteries. During liver ontogenesis, the development of the hepatic artery appears to be modulated by unknown signals originating from the bile duct.

Norberto C. Chávez‐Tapia, Felix I. Tellez‐Avila, Misael Uribe – 26 January 2008

Michael W. Fried, Teerha Piratvisuth, George K. K. Lau, Patrick Marcellin, Wan‐Cheng Chow, Graham Cooksley, Kang‐Xian Luo, Seung Woon Paik, Yun‐Fan Liaw, Peter Button, Matei Popescu – 26 January 2008 – The aims of this study were to evaluate the usefulness of quantitative hepatitis B e antigen (HBeAg) values for predicting HBeAg seroconversion in patients treated with peginterferon alfa‐2a and to assess the dynamic changes in quantitative HBeAg during therapy, compared with conventional measures of serum hepatitis B virus DNA.

Umberto Arena, Francesco Vizzutti, Giampaolo Corti, Silvia Ambu, Cristina Stasi, Silvia Bresci, Stefania Moscarella, Vieri Boddi, Antonio Petrarca, Giacomo Laffi, Fabio Marra, Massimo Pinzani – 26 January 2008 – Liver tissue alterations other than fibrosis may have an impact on liver stiffness measurement. In this study we evaluated 18 patients without a previous clinical history of liver disease, consecutively admitted for acute viral hepatitis.

Masaaki Shiina, Barbara Rehermann – 26 January 2008 – Previous studies suggested a functional impairment of dendritic cells (DCs) in patients with chronic hepatitis C. To investigate whether this effect was mediated by a direct interaction of hepatitis C virus (HCV) with DCs, we studied the effects of infectious cell culture–produced hepatitis C virus (HCVcc) on peripheral blood mononuclear cells (PBMCs), ex vivo isolated plasmacytoid, and myeloid DCs and in vitro generated monocyte‐derived DCs of healthy blood donors.

Jeremy F L Cobbold, Simon D Taylor‐Robinson – 26 January 2008

Pierre Bedossa, Rami Moucari, Emna Chelbi, Tarik Asselah, Valerie Paradis, Michel Vidaud, Dominique Cazals‐Hatem, Nathalie Boyer, Dominique Valla, Patrick Marcellin – 26 January 2008

Humberto Reyes – 26 January 2008

Philippe Colson, Nabil Brouk, Frédérique Lembo, Paul Castellani, Catherine Tamalet, René Gérolami – 26 January 2008