Inhibition of Kupffer cell‐mediated early proinflammatory response with carbon monoxide in transplant‐induced hepatic ischemia/reperfusion injury in rats

Koji Tomiyama, Atsushi Ikeda, Shinya Ueki, Atsunori Nakao, Donna B. Stolz, Yasushi Koike, Amin Afrazi, Chandrashekhar Gandhi, Daisuke Tokita, David A. Geller, Noriko Murase – 29 October 2008 – Proinflammatory responses play critical roles in hepatic ischemia/reperfusion (I/R) injury associating with liver transplantation (LTx), and carbon monoxide (CO) can effectively down‐regulate them.

Metabolic syndrome in liver transplantation: Relation to etiology and immunosuppression

Giampaolo Bianchi, Giulio Marchesini, Rebecca Marzocchi, Antonio D. Pinna, Marco Zoli – 29 October 2008 – Excessive weight gain, hypertension, hyperlipidemia, and diabetes are frequently observed in patients having undergone liver transplantation (LTx). These alterations are probably multifactorial in origin, and cluster to generate a metabolic syndrome (MS), increasing the risk of cardiovascular events.

A J‐shaped subcostal incision reduces the incidence of abdominal wall complications in liver transplantation

Joos Heisterkamp, Hendrik A. Marsman, Hassan Eker, Herold J. Metselaar, Hugo W. Tilanus, Geert Kazemier – 29 October 2008 – A novel J‐shaped incision for liver transplantation was introduced in attempt to reduce the wound‐related complication rate while maintaining comparable access. Some 58 consecutive patients with the classic Mercedes incision were compared with the following 60 consecutive patients with a J‐shaped incision. Nine of 60 patients (15%) with a J‐shaped incision were converted to an extensive incision.

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