John P. Norvell, Andres T. Blei, Borko D. Jovanovic, Josh Levitsky – 27 September 2007 – Hepatitis is a rare complication of herpes simplex virus (HSV), often leading to acute liver failure (ALF), liver transplantation (LT), and/or death. Our aim was to identify variables associated with either survival or progression (death/LT), based on an analysis of cases in the literature and our institution. A total of 137 cases (132 literature, 5 institutional) of HSV hepatitis were identified. The main features at clinical presentation were fever (98%), coagulopathy (84%), and encephalopathy (80%).

John Rodriguez, Katherine Casper, Gregory Smallwood, Andrei Stieber, Carlos Fasola, Jennifer Lehneman, Thomas Heffron – 27 September 2007 – We present a case report of a cytomegalovirus (CMV)‐seronegative, 58‐year‐old male who received a CMV‐seropositive donor liver transplant without CMV prophylaxis. On postoperative day 30, the patient developed primary CMV disease that responded to ganciclovir. On postoperative day 114, however, he was diagnosed with recurrent CMV infection.

Sven Jonas, Peter Neuhaus – 27 September 2007

Àngels Escorsell, Antoni Mas, Manuel de la Mata, Spanish Group for the Study of Acute Liver Failure – 27 September 2007 – The cause of acute liver failure (ALF) is a major determinant of its outcome. Acetaminophen (paracetamol) overdose is a leading cause of ALF in some developed countries, whereas in others, such as Spain, it is extremely rare. To analyze the etiology, characteristics, and outcome of ALF in Spain, we performed a retrospective analysis of 267 patients whom we observed from 1992 to 2000.

Joseph C. Yarze, David M. Markowitz – 27 September 2007

Julie Polson, William M. Lee – 27 September 2007

Johannes Hadem – 27 September 2007

James V. Guarrera, Barbara J. Alkofer, Nikki Feirt, Rodrigo Sandoval, Benjamin Samstein, Elton T. Smith, David Marshman, Chris Cogswell, Jason Vannatta, Robert S. Brown, Jean C. Emond, John F. Renz – 27 September 2007

S. Simona Jakab, Victor J. Navarro, Beth W. Colombe, Constantine Daskalakis, Steven K. Herrine, Simona Rossi – 27 September 2007 – Human leukocyte antigen (HLA) compatibility has no clinically significant impact in cadaveric liver transplantation. Less is known regarding living‐donor liver transplantation (LDLT). Our prior analysis of the Organ Procurement and Transplantation Network (OPTN) database suggested a higher graft failure rate in patients who underwent LDLT from donors with close HLA match.

Atul Humar, Kenneth Washburn, Richard Freeman, Carlos V. Paya, Houria Mouas, Emma Alecock, Raymund R. Razonable, PV16000 Study Group – 27 September 2007 – Hepatitis C virus (HCV) has been proposed to have immunomodulatory effects in transplant recipients and may promote herpesvirus reactivation. To assess this, we compared the incidence of herpesvirus reactivation in HCV‐positive and HCV‐negative liver transplant recipients.