Amy A. Dan, Jillian B. Kallman, Ragini Srivastava, Zahra Younoszai, Amy Kim, Zobair M. Younossi – 27 February 2008 – Assessment of health‐related quality of life (HRQL) and health utilities have become important aspects of clinical research. Patient‐derived utility adjustments are frequently used in economic analysis. Although HRQL has been frequently studied among patients with liver disease, extensive data on the health utilities of patients with liver disease are not available. Recently, SF‐6D has been developed to obtain utility scores from the widely used Short Form 36 questionnaire.

Junji Komori, Hiroyuki Marusawa, Takafumi Machimoto, Yoko Endo, Kazuo Kinoshita, Tadayuki Kou, Hironori Haga, Iwao Ikai, Shinji Uemoto, Tsutomu Chiba – 27 February 2008 – Chronic inflammation plays a critical role in oncogenesis in various human organs. Epidemiological studies have demonstrated that patients with primary sclerosing cholangitis have a predisposition to develop cholangiocarcinoma (CC). However, the molecular mechanisms that account for the development of bile duct carcinomas are not well defined.

Koichi Matsuzaki, Iwata Ozaki – 27 February 2008

Edwin K. Kuffner, Jeffrey S. Baggish – 27 February 2008

27 February 2008

Chun‐Ping Cui, Da‐Jin Zhang, Bing‐Xing Shi, Shao‐Jun Du, Dan‐Li Wu, Ping Wei, Gen‐Shen Zhong, Zi‐Kuan Guo, Yang Liu, Li‐Sheng Wang, Chu‐Tse Wu – 27 February 2008 – Hepatic stimulating substance (HSS) was first isolated from weanling rat liver in 1975 and found to stimulate hepatic DNA synthesis both in vitro and in vivo. Since then, mammalian and human HSS have been investigated for their potential to treat hepatic diseases. However, the essential nature in composition and structure of HSS remain puzzling because HSS has not been completely purified.

Tetsuji Fujita – 27 February 2008

William Bernal, Francesca Meda, Yun Ma, Dimitrios P. Bogdanos, Diego Vergani – 27 February 2008

Jürgen Treckmann, Thomas Minor, Stefano Saad, Arzu Özcelik, Massimo Malagó, Christoph Erich Broelsch, Andreas Paul – 27 February 2008 – Retrograde oxygen persufflation as a supplement of cold storage during the preservation period has the potential to better utilize ischemically damaged marginal livers in the experimental setting. Retrograde oxygen persufflation was applied in selected livers to demonstrate feasibility in the clinical setting and to investigate potential beneficial effects.

Antonia D'Errico‐Grigioni, Michelangelo Fiorentino, Francesco Vasuri, Elisa Gruppioni, Benedetta Fabbrizio, Nicola Zucchini, Giorgio Ballardini, Cristina Morelli, Antonio Daniele Pinna, Walter Franco Grigioni – 27 February 2008 – We compared tissue hepatitis C virus (HCV) RNA polymerase chain reaction quantification and HCV immunohistochemistry (IHC) to histology in biopsy tissues in order to differentiate between acute rejection and HCV hepatitis recurrence early after orthotopic liver transplantation (OLT).