Cihan Duran, Burcin Taner, Murat Dayangac, Baris Akin, Deniz Balci, Zahide Kurt, Refik Killi, Yildiray Yuzer, Yaman Tokat – 30 July 2007

Marie Laryea, Kymberly D. Watt, Michele Molinari, Mark J. Walsh, Vivian C. McAlister, Paul J. Marotta, Bjorn Nashan, Kevork M. Peltekian – 30 July 2007 – Cardiac and cerebral vascular diseases are leading causes of morbidity and death in solid organ transplant recipients. Immunosuppressant drugs are associated with dyslipidemia, hypertension, and hyperglycemia, which along with obesity are the main features of metabolic syndrome. In the nontransplant population, metabolic syndrome is associated with increased risk for major vascular complications.

Yasuhiko Sugawara, Sumihito Tamura – 30 July 2007

Birger Wolff, Klaus Machill, Detlef Schumacher, Ilona Schulzki – 30 July 2007 – Acute decompensation of chronically stable alcoholic liver disease (ALD) is the most common cause of terminal liver failure in developed countries. Molecular adsorbent recirculation system (MARS) is increasingly used as artificial liver support to facilitate spontaneous organ recovery. However, the experience to date and the evidence to justify this therapeutic strategy in acutely decompensated ALD are still insufficient.

Fabio Piscaglia, Alice Gianstefani, Roberto Righini, Luigi Bolondi – 30 July 2007

Ziv Ben‐Ari, Orit Pappo, Yelena Cheporko, Natali Yasovich, Daniel Offen, Asher Shainberg, Dorit Leshem, Jacquelin Sulkes, Bernardo A. Vidne, Edith Hochhauser – 30 July 2007 – Apoptosis appears to be a central mechanism of cell death following reperfusion of the ischemic liver. The aim of this study was to determine the effect of decreased expression of the proapoptotic Bax gene on hepatic apoptotic warm ischemia/reperfusion (I/R) injury. Three groups of mice were studied: homozygotic knockout mice (Bax−/−); heterozygotic (Bax+/−); and wild type (Bax+/+).

Mitsuhisa Takatsuki, Susumu Eguchi, Takashi Kanematsu – 30 July 2007

Burckhardt Ringe, Ralph J. Petrucci, Humberto E. Soriano, James C. Reynolds, William C. Meyers – 30 July 2007 – In children with acute hepatic failure, it has been suggested to offer living donor transplantation to all parents when a deceased donor organ can not be provided. Ethically, living related donation is coercive by its very nature, especially in emergencies. We report a 36‐year‐old woman who died from a drug overdose 57 days after living donor liver resection. The recipient was her 3‐year‐old son, who experienced acute hepatic failure as a result of acetaminophen intoxication.

Roman Perri, Maha Assi, Jayant Talwalkar, Julie Heimbach, William Hogan, S. Breanndan Moore, Charles B. Rosen – 30 July 2007 – Graft‐vs.‐host disease (GVHD) is a rare, serious complication of orthotopic liver transplantation (OLT). We have treated 5 patients to date with GVHD after OLT. A total of 78 patients worldwide have been reported to have experienced this complication. The means by which GVHD after OLT has been managed is guided by experience with the more common GVHD that occurs after stem cell transplantation.

Munira Hussain, Consuelo Soldevila‐Pico, Sukru Emre, Velimir Luketic, Anna S.F. Lok – 30 July 2007 – Previous studies reported that hepatitis B virus (HBV) deoxyribonucleic acid (DNA) can be detected in livers of patients who received transplants for hepatitis B despite the absence of serological markers of HBV recurrence. Quantification of HBV DNA was not performed and presence of covalently closed circular (ccc) DNA was not analyzed in most studies.