Elevated fractional donor‐derived cell‐free DNA during subclinical graft injury after liver transplantation

Anna K. Baumann, Julia Beck, Theresa Kirchner, Björn Hartleben, Ekkehard Schütz, Michael Oellerich, Heiner Wedemeyer, Elmar Jaeckel, Richard Taubert – 15 April 2022 – Personalized immunosuppression (IS) promises to improve the balance of necessary control of alloreactivity and dose‐dependent adverse effects of long‐term IS such as kidney insufficiency, infections, and malignancies.

Distinct responsiveness to rifaximin in patients with hepatic encephalopathy depends on functional gut microbial species

Yoshimi Yukawa‐Muto, Tomonori Kamiya, Hideki Fujii, Hiroshi Mori, Atsushi Toyoda, Ikuya Sato, Yusuke Konishi, Akiyoshi Hirayama, Eiji Hara, Shinji Fukuda, Norifumi Kawada, Naoko Ohtani – 15 April 2022 – Hepatic encephalopathy (HE) is the neuropsychiatric complication of liver cirrhosis (LC). The influence of gut microbiota on HE pathogenesis has been suggested but not precisely elucidated. Here, we investigate how the gut microbial profile changed in patients with HE to clarify the functional gut microbial species associated with HE.

Tripartite motif‐containing protein 31 confers protection against nonalcoholic steatohepatitis by deactivating mitogen‐activated protein kinase kinase kinase 7

Min‐Xuan Xu, Jun Tan, Chen‐Xu Ge, Wei Dong, Li‐Ting Zhang, Lian‐Cai Zhu, Jun‐Jie Zhao, Long‐Yan Wang, Jin Liu, Hao Wei, Yan Sun, Xian‐Ling Dai, Qin Kuang, Yan‐Liang Li, Han Li, Jun‐Yan Liu, Lei Zou, Ran‐Ran Liang, Chu‐Feng Zhang, Juan Xu, Bo‐Chu Wang – 15 April 2022

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