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Vladimir V. Loukachov, Karel A. Dort, Robin Erken, Henk W. Reesink, Neeltje A. Kootstra – 22 March 2022
Letter to the editor: Alu‐PCR design may have compromised detection of integrated core HBV DNA
Gustaf E. Rydell, Johan Ringlander, Simon B. Larsson, Kristoffer Hellstrand, Magnus Lindh – 22 March 2022
Single‐cell transcriptomics reveals conserved cell identities and fibrogenic phenotypes in zebrafish and human liver
Joshua K. Morrison, Charles DeRossi, Isaac L. Alter, Shikha Nayar, Mamta Giri, Chi Zhang, Judy H. Cho, Jaime Chu – 21 March 2022 – The mechanisms underlying liver fibrosis are multifaceted and remain elusive with no approved antifibrotic treatments available. The adult zebrafish has been an underutilized tool to study liver fibrosis. We aimed to characterize the single‐cell transcriptome of the adult zebrafish liver to determine its utility as a model for studying liver fibrosis.
Hepatic kinome atlas: An in‐depth identification of kinase pathways in liver fibrosis of humans and rodents
Justin F. Creeden, Zachary A. Kipp, Mei Xu, Robert M. Flight, Hunter N. B. Moseley, Genesee J. Martinez, Wang‐Hsin Lee, Khaled Alganem, Ali S. Imami, Megan R. McMullen, Sanjoy Roychowdhury, Atta M. Nawabi, Jennifer A. Hipp, Samir Softic, Steven A. Weinman, Robert McCullumsmith, Laura E. Nagy, Terry D. Hinds – 20 March 2022
Association between social determinants of health and rates of liver transplantation in individuals with cirrhosis
Jennifer A. Flemming, Hala Muaddi, Maja Djerboua, Paula Neves, Gonzalo Sapisochin, Nazia Selzner – 20 March 2022
Acute cellular rejection in liver transplantation recipients following coronavirus disease 2019 vaccination
Rujittika Mungmunpuntipantip, Viroj Wiwanitkit – 20 March 2022
A pan‐genotype hepatitis C virus viral vector vaccine generates T cells and neutralizing antibodies in mice
Timothy Donnison, Joey McGregor, Senthil Chinnakannan, Claire Hutchings, Rob J. Center, Pantelis Poumbourios, Paul Klenerman, Heidi E. Drummer, Eleanor Barnes – 20 March 2022
Donor–recipient human leukocyte antigen A mismatching is associated with hepatic artery thrombosis, sepsis, graft loss, and reduced survival after liver transplant
Christopher Bricogne, Neil Halliday, Raymond Fernando, Emmanuel A. Tsochatzis, Brian R. Davidson, Mark Harber, Rachel H. Westbrook – 20 March 2022 – Human leukocyte antigen (HLA) matching is not routinely performed for liver transplantation as there is no consistent evidence of benefit; however, the impact of HLA mismatching remains uncertain. We explored the effect of class I and II HLA mismatching on graft failure and mortality. A total of 1042 liver transplants performed at a single center between 1999 and 2016 with available HLA typing data were included.
Preliminary evidence of safety and tolerability of atezolizumab plus bevacizumab in patients with hepatocellular carcinoma and Child‐Pugh A and B cirrhosis: A real‐world study
Antonio D’Alessio, Claudia Angela Maria Fulgenzi, Naoshi Nishida, Martin Schönlein, Johann Felden, Kornelius Schulze, Henning Wege, Vincent E. Gaillard, Anwaar Saeed, Brooke Wietharn, Hannah Hildebrand, Linda Wu, Celina Ang, Thomas U. Marron, Arndt Weinmann, Peter R. Galle, Dominik Bettinger, Bertram Bengsch, Arndt Vogel, Lorenz Balcar, Bernhard Scheiner, Pei‐Chang Lee, Yi‐Hsiang Huang, Suneetha Amara, Mahvish Muzaffar, Abdul Rafeh Naqash, Antonella Cammarota, Nicola Personeni, Tiziana Pressiani, Rohini Sharma, Matthias Pinter, Alessio Cortellini, Masatoshi Kudo, Lorenza Rimassa, David J.
Preservation solutions for static cold storage in donation after circulatory death and donation after brain death liver transplantation in the United States
Thomas G. Cotter, Matthew A. Odenwald, Angelica Perez‐Gutierrez, Kumar Jayant, Diego DiSabato, Michael Charlton, John Fung – 20 March 2022 – Static cold preservation remains the cornerstone for storing donor livers following procurement; however, the choice between University of Wisconsin solution (UW) and histidine‐tryptophan‐ketoglutarate solution (HTK) remains controversial. Recent International Liver Transplantation Society (ILTS) guidelines have recommended avoiding HTK for donation after circulatory death (DCD) grafts based on older reports.