LiverLearning®: 2022 Webinar: Applications of TIPS for Portal Hypertension: Entering a New Era

This webinar will address endovascular management of portal hypertensive complications using TIPS. Speakers will assess evidence for the use of TIPS in the setting of portal and mesenteric vein thromboses and how this may impact portal HTN, survival, as well as transplant outcomes. Speakers will also discuss the standard and emerging indications for TIPS as well as future directions for TIPS management in portal HTN.Virginia Hernandez-Gea Virginia Hernández-Gea, MD, PhD is a interventional hepatologist at the liver unit at hospital clinic.

Transmembrane channel activity in human hepatocytes and cholangiocytes derived from induced pluripotent stem cells

Rodrigo M. Florentino, Qin Li, Michael C. Coard, Nils Haep, Takashi Motomura, Ricardo Diaz‐Aragon, Lanuza A. P. Faccioli, Sriram Amirneni, Zehra N. Kocas‐Kilicarslan, Alina Ostrowska, James E. Squires, Andrew P. Feranchak, Alejandro Soto‐Gutierrez – 14 March 2022 – The initial creation of human‐induced pluripotent stem cells (iPSCs) set the foundation for the future of regenerative medicine. Human iPSCs can be differentiated into a variety of cell types in order to study normal and pathological molecular mechanisms.

The fundamentals of sex‐based disparity in liver transplantation: Understanding can lead to change

Noreen Singh, Kymberly D. Watt, Rahima A. Bhanji – 14 March 2022 – Liver transplantation (LT) is the definitive treatment for end‐stage liver disease. Unfortunately, women are disadvantaged at every stage of the LT process. We conducted a literature review to increase the understanding of this disparity. Hormonal differences, psychological factors, and Model for End‐Stage Liver Disease (MELD) score inequalities are some pretransplantation factors that contribute to this disparity.

C‐C motif chemokine ligand 5 confines liver regeneration by down‐regulating reparative macrophage‐derived hepatocyte growth factor in a forkhead box O 3a–dependent manner

Miao Huang, Junzhe Jiao, Hao Cai, Yichi Zhang, Yuhan Xia, Jiacheng Lin, Zhi Shang, Yihan Qian, Fang Wang, Hailong Wu, Xiaoni Kong, Jinyang Gu – 14 March 2022

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