Fibrous tumor‐liver interface in large hepatic neoplasms: Its significance for tumor resection and enucleation

Arthur Zimmermann, Hans‐Ulrich Baer – 1 May 1996 – Based on the clinical observation that large tumors located in the liver may be resected or enucleated with relative ease, the present retrospective study aimed at the detailed assessment of the tumor/liver interface in large hepatic neoplasms. For this purpose, a systematic light microscopic and immunohistochemical study on resection specimens of 10 giant hemangiomas, 10 hepatocellular carcinomas, and 9 liver metastases was performed.

Role of Kupffer cells in arresting circulating tumor cells and controlling metastatic growth in the liver

L G Bayon, M A Izquierdo, I Sirovich, N van rooijen, R H Beelen, S Meijer – 1 May 1996 – Metastasis to the liver is a common event in clinical oncology. Blood‐borne tumor cells (TCs) arriving to the liver sinusoids run into a special vascular bed. The lining of liver sinusoids is shared by Kupffer cells (KCs) and endothelial cells. KCs, liver‐fixed macrophages, are responsible for detection and removal of “non‐self” particles.

Hepatitis C virus RNA in peripheral blood mononuclear cells: Comparing acute and chronic hepatitis C virus infection

T Chang, K Young, Y Yang, H Lei, H Wu – 1 May 1996 – Hepatitis C virus (HCV) can infect peripheral blood mononuclear cells (PBMC) of patients with chronic HCV infection. No data are available on PBMC testing for HCV RNA in acute hepatitis C. This study investigated the presence of HCV RNA in PBMC of patients with acute posttransfusion hepatitis C, compared with those with chronic HCV infection.

Prognosis of small hepatocellular carcinoma (less than 3 cm) after percutaneous acetic acid injection: Study of 91 cases

K Ohnishi, F Nomura, S Ito, K Fujiwara – 1 May 1996 – To assess the efficacy of ultrasound (US)‐guided percutaneous acetic acid (in concentrations of 15%, 20%, 30%, 40%, and 50%) injection for small hepatocellular carcinomas (HCCs) for long‐term prognosis, percutaneous acetic acid injection using 15% to 50% acetic acid was performed in 91 patients with one to four HCCs smaller than 3 cm during the past 6.5 years. During the series of treatment sessions for each patient, the same concentration of acetic acid was used.

Auxiliary liver transplantation: Regeneration of the native liver and outcome in 30 patients with fulminant hepatic failure–a multicenter European study

M Chenard‐Neu, K Boudjema, J Bernuau, C Degott, J Belghiti, D Cherqui, V Costes, J Domergue, F Durand, J Erhard, B De Hemptinne, G Gubernatis, A Hadengue, J Kemnitz, M McCarthy, H Maschek, G Mentha, K Oldhafer, B Portmann, M Praet, J Ringers, X Rogiers, L Rubbia, S Schalm, F T Kate, O Terpstra, B Van Hoek, R Williams, E Zafrani, J Cinqualbre, P Wolf, D Jaeck, J Bellocq – 1 May 1996 – Auxiliary liver transplantation (LT) is a special procedure of LT which could be proposed to patients with fulminant hepatic failure (FHF) and has for aim that complete regeneration of the native liver (NL) lef

Heat serum inactivation as a mandatory procedure for antiactin antibody detection in cell culture

E L Cancado, L S Vilas‐Boas, C P Abrantes‐Lemos, N F Novo, G Porta, L C Da Silva, A A Laudanna – 1 May 1996 – In autoimmune hepatitis (AIH), the smooth‐muscle antibody is specific for polymerized actin. Detection of antiactin antibody (AAA) has been hampered by technical problems. We have investigated AAA in 30 sera from patients with liver diseases and smooth‐muscle antibody. AAA was detected by indirect immunofluorescence in 1:40, 1:80, and 1:160 dilutions.

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