Forum on critical care issues in liver transplantation: Neurological concerns

David J. Plevak – 1 September 1995 – This edition of “The Crucible” contains the first installment of what we hope will become an ongoing discussion of critical care issues in liver transplantation. After considering an agenda of salient critical care topics, we chose to inaugurate the Critical Care Forum with this discussion on neurological concerns. Intensivists, transplant surgeons, and others involved in the immediate postoperative care of liver transplant recipients generally do not expect a serious neurological setback after transplantation.

Organellar clusters formed by mitochondrial‐rough endoplasmic reticulum associations: An ordered arrangement of mitochondria in hepatocytes

Joseph Cascarano, Patricia A. Chambers, Eileen Schwartz, Parvoneh Poorkaj, Roy E. Gondo – 1 September 1995 – Our objective was to determine if mitochondrial‐rough endoplasmic reticulum (mt‐RER) associations provide for an ordered arrangement of mitochondria in the cell. If such an ordered arrangement exists, it might be manifested by grouping of mitochondria according to size and biochemical properties. Liver homogenate was subjected to rate zonal centrifugation for fractionating mitochondrial clusters. These clusters were then examined for morphological and biochemical characteristics.

Liver transplantation and the alcoholic patient:Medical, surgical, and psychosocial issues by Michael R. Lucey, Michael R. Lucey, Robert M. Marian, Thomas P. Beresford. 134 pp. New York, NY: Cambridge University Press, 1994 $49.95

In vitro activation of woodchuck lymphocytes measured by radiopurine incorporation and interleukin‐2 production: Implications for modeling immunity and therapy in hepatitis B virus infection

Paul J. Cote, John L. Gerin – 1 September 1995 – Cellular immune responses to hepatitis B virus (HBV) play an important role in the resolution of acute infection. They also influence the course of chronic infection and disease but are inadequate to completely clear the infection. Woodchuck hepatitis virus (WHV) infection of the woodchuck can provide a model to study these processes.

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