Qin Su, Yan‐Fang Liu, Jin‐Feng Zhang, Sui‐Xiang Zhang, De‐Fang Li, Jia‐Ji Yang – 1 October 1994 – Expression of insulin‐like growth factor II in two human hepatocellular carcinoma cell lines and in hepatitis B, cirrhosis and hepatocellular carcinoma in 419 cases were investigated, and its relationship with the expression of hepatitis B virus x gene was studied by means of immunohistochemical and electron microscopic techniques. The results demonstrated that hepatocellular carcinoma cells (SMMC 7721 and QGY 7703) in culture could express insulin‐like growth factor II.

Steven M. Strasberg, Todd K. Howard, Ernesto P. Molmenti, Martin Hertl – 1 October 1994 – Initial poor function and primary nonfunction are important problems in clinical transplantation. The incidence of primary nonfunction is about 6% and that of initial poor function is about 15%. Grafts with initial poor function have a higher graft failure rate in the first 3 mo after transplantation. Severe steatosis and cold preservation in University of Wisconsin solution for over 30 hr will alone cause primary nonfunction.

Stefano Milani, Cecilia Grappone, Giulia Pellegrini, Detlef Schuppan, Hermann Herbst, Antonio Calabró, Alessandro Casini, Massimo Pinzani, Calogero Surrenti – 1 October 1994 – We have analyzed the distribution, gene expression and cellular origin of undulin, a large extracellular matrix glycoprotein associated with mature collagen fibrils, in human liver by immunohistochemistry, Northern‐blot analysis and in situ hybridization. In normal liver, undulin was distributed as densely packed fibers in portal tract stroma, and as fine fibers along sinusoids, and around central veins.

Kenneth Jensen, Christian Gluud – 1 October 1994 – To aid understanding of markers of disease and predictors of outcome in alcohol‐exposed systems, we undertook a literature survey of more than 700 articles to view the morphological characteristics and the clinical and experimental epidemiology of the Mallory body. Mallory bodies are filaments of intermediate diameter that contain intermediate filament components (e.g., cytokeratins) observable by conventional light microscopy or immunohistochemical methods, identical in structure regardless of initiating factors or putative pathogenesis.

J. Michael Henderson, Norman D. Grace – 1 October 1994

William R. Brugge – 1 October 1994 – Background/Aims: Endoscopic ultrasonography is a promising procedure for the diagnosis of extrahepatic cholestasis. Accuracy for the diagnosis of choledocholithiasis by ultrasonography and computed tomography were prospectively compared with endoscopic ultrasonography in 62 consecutive patients.

Raymond S. Koff – 1 October 1994

Patrice Beaudry, Antoine Hadengue, Jacques Callebert, Christophe Gaudin, Hany Soliman, Richard Moreau, Jean Marie Launay, Didier Lebrec – 1 October 1994 – Serotoninergic mechanisms are thought to play a role in portal hypertension. Because this biomine is metabolized by the liver, peripheral blood and plasma levels of 5‐hydroxytryptamine and 5‐hydroxyindole acetic acid (the main metabolite of 5‐hydroxytryptamine) were measured in 30 patients with cirrhosis.

Marshall J. Orloff, Richard H. Bell, Mark S. Orloff, William G. M. Hardison, A. Gerson Greenburg – 1 October 1994 – A prospective randomized trial was conducted in unselected, consecutive patients with bleeding esophageal varices resulting from cirrhosis comparing (1) emergency portacaval shunt performed within 8 hr of initial contact (21 patients) with (2) emergency medical therapy (intravenous vasopressin and esophageal balloon tamponade) followed in 9 to 30 days by elective portacaval shunt in survivors (22 patients).

A. Guan Lim, Riadh P. Jazrawi, Hafez A. Ahmed, Joanne H. Levy, Massimo Zuin, Andrew C. Douds, J. Douglas, Tim C. Northfield – 1 October 1994 – Intercellular adhesion molecule—1, strongly expressed on the interlobular and proliferating bile ducts in primary biliary cirrhosis, is important in the migration and adhesion of inflammatory cells from the circulation to these structures. A soluble form has been found to be elevated in serum in primary biliary cirrhosis.