Sex‐Specific Regulation of Interferon‐γ Cytotoxicity in Mouse Liver by Autophagy
Yang Shen, Francesca Cingolani, Shoaib Ahmad Malik, Jing Wen, Yunshan Liu, Mark J. Czaja – 11 June 2021
Medicaid Expansion Association With End‐Stage Liver Disease Mortality Depends on Leniency of Medicaid Hepatitis C Virus Coverage
Nabeel A. Wahid, Jihui Lee, Alyson Kaplan, Brett E. Fortune, Monika M. Safford, Robert S. Brown, Russell Rosenblatt – 11 June 2021 – The Affordable Care Act expanded Medicaid around the same time that direct‐acting antivirals became widely available for the treatment of hepatitis C virus (HCV). However, there is significant variation in Medicaid HCV treatment eligibility criteria between states. We explored the combined effects of Medicaid expansion and leniency of HCV coverage under Medicaid on liver outcomes.
The Role of Ex Situ Hypothermic Oxygenated Machine Perfusion and Cold Preservation Time in Extended Criteria Donation After Circulatory Death and Donation After Brain Death
Damiano Patrono, Raffaele Potenza, Marinella Zanierato, Renato Romagnoli – 11 June 2021
Had Anyone Considered the Donors? Fertility and Pregnancy Outcomes Among Female Living Donors
Tatyana Kushner, Nancy Reau – 11 June 2021
Living Donor Liver Transplantation in Acute‐on‐Chronic Liver Failure: Encouraging Outcomes But With Important Caveats
Thomas G. Cotter, Vinay Sundaram – 11 June 2021
Utility of Preoperative Computed Tomography–Based Body Metrics in Relation to Postoperative Complications in Pediatric Liver Transplantation Recipients
Martijn V. Verhagen, Stef Levolger, Jan Binne Hulshoff, Maureen J. M. Werner, Hubert P. J. Doef, Alain R. Viddeleer, Ruben H. Kleine, Robbert J. Haas – 11 June 2021 – Computed tomography (CT)‐derived body metrics such as skeletal muscle index (SMI), psoas muscle index (PMI), and subcutaneous fat area index (ScFI) are measurable components of sarcopenia, frailty, and nutrition. While these body metrics are advocated in adults for predicting postoperative outcomes after liver transplantation (LT), little is known about their value in pediatric populations.
Had Anyone Considered the Donors? Fertility and Pregnancy Outcomes Among Female Living Donors
Tatyana Kushner, Nancy Reau – 11 June 2021
HATs Off to Clot Blockers: A Potential New Role for Statins After Transplantation
Prashanth Francis, Lisa Forman – 11 June 2021
Interleukin‐10 and Transforming Growth Factor‐β Cytokines Decrease Immune Activation During Normothermic Ex Vivo Machine Perfusion of the Rat Liver
Kristin N. Carlson, Juliana Pavan‐Guimaraes, Joshua C. Verhagen, Peter Chlebeck, Bret Verhoven, Heather Jennings, Feridoon Najmabadi, Yongjun Liu, William Burlingham, Christian M. Capitini, David P. Al‐Adra – 11 June 2021 – Normothermic ex vivo liver perfusion (NEVLP) is a novel system for organ preservation that may improve over static cold storage clinically and offers the chance for graft modification prior to transplantation.
Inclusive Quantification Assay of Serum Des‐γ‐Carboxyprothrombin Proteoforms for Hepatocellular Carcinoma Surveillance by Targeted Mass Spectrometry
Jihyeon Lee, Young‐Suk Lim, Jeong‐Hoon Lee, Geum‐Youn Gwak, Misol Do, Injoon Yeo, Dongyoon Shin, Dohyun Han, Taesung Park, Youngsoo Kim – 11 June 2021 – Hepatocellular carcinoma (HCC) is a malignant cancer with one of the highest mortality rates. Des‐γ‐carboxyprothrombin (DCP) is an HCC serologic surveillance marker that can complement the low sensitivity of alpha‐fetoprotein (AFP). DCP exists in the blood as a mixture of proteoforms from an impaired carboxylation process at glutamic acid (Glu) residues within the N‐terminal domain.