The Matrisome Genes From Hepatitis B–Related Hepatocellular Carcinoma Unveiled

Wei Chen, Romain Desert, Xiaodong Ge, Hui Han, Zhuolun Song, Sukanta Das, Dipti Athavale, Hong You, Natalia Nieto – 15 June 2021 – Chronic hepatitis B virus (HBV) infection changes the composition of the extracellular matrix (ECM) and enables the onset and progression of hepatocellular carcinoma (HCC). The ensemble of ECM proteins and associated factors is a major component of the tumor microenvironment. Our aim was to unveil the matrisome genes from HBV‐related HCC.

Extensive Health Care Utilization and Costs of an Early Liver Transplantation Program for Alcoholic Hepatitis

Gene Y. Im, Alexander S. Vogel, Sander Florman, Jonathan Nahas, Scott L. Friedman, Sarah Aqui, Laura Ford, Omar Mirza, Leona Kim‐Schluger, Thomas D. Schiano – 15 June 2021 – Early liver transplantation (LT) for severe alcoholic hepatitis (AH) is a rescue therapy for highly selected patients with favorable psychosocial profiles not responding to medical therapy. Given the expected increase of AH candidate referrals requiring complex care and comprehensive evaluations, increased workload and cost might be expected from implementing an early LT program for AH but have not been determined.

The Prognostic Utility of Intraoperative Allograft Vascular Inflow Measurements in Donation After Circulatory Death Liver Transplantation

Amit Nair, Kazunari Sasaki, Teresa Diago Uso, Giuseppe D’Amico, Bijan Eghtesad, Federico Aucejo, Choon Hyuck David Kwon, Masato Fujiki, Charles Miller, Koji Hashimoto, Cristiano Quintini – 15 June 2021 – Donation after circulatory death (DCD) liver transplantation improves deceased donor liver use and decreases waitlist burden, albeit at an increased risk of biliary complications and inferior graft survival. Employing liver vascular inflow measurements intraoperatively permits allograft prognostication.

Subjective Cognition Reported by Caregivers Is Correlated With Objective Cognition in Liver Transplant Recipients

Dami Ko, Mary S. Dietrich, Katherine A. Gifford, Sheila H. Ridner – 15 June 2021 – Objective cognitive assessments, a gold standard diagnostic tool for cognitive impairment, may not be feasible in busy liver transplantation (LT) practice because they are often time consuming. This study determined whether subjective cognition, patients’ self‐ratings and/or caregivers’ ratings of patients’ cognition, reflects objective cognition in LT recipients.

Impact of Public Health Policies on Alcohol‐Associated Liver Disease in Latin America: An Ecological Multinational Study

Luis Antonio Díaz, Francisco Idalsoaga, Eduardo Fuentes‐López, Andrea Márquez‐Lomas, Carolina A. Ramírez, Juan Pablo Roblero, Roberta C. Araujo, Fátima Higuera‐de‐la‐Tijera, Luis Guillermo Toro, Galo Pazmiño, Pedro Montes, Nelia Hernandez, Manuel Mendizabal, Oscar Corsi, Catterina Ferreccio, Mariana Lazo, Mayur Brahmania, Ashwani K. Singal, Ramon Bataller, Marco Arrese, Juan Pablo Arab – 15 June 2021

Chyme Reinfusion Restores the Regulatory Bile Salt–FGF19 Axis in Patients With Intestinal Failure

Kiran V.K. Koelfat, Denis Picot, Xinwei Chang, Mireille Desille‐Dugast, Hans M. Eijk, Sander M.J. Kuijk, Martin Lenicek, Sabrina Layec, Marie Carsin, Laurence Dussaulx, Eloi Seynhaeve, Florence Trivin, Laurence Lacaze, Ronan Thibault, Frank G. Schaap, Steven W.M. Olde Damink – 15 June 2021

Comparison of HBV RNA and Hepatitis B Core Related Antigen With Conventional HBV Markers Among Untreated Adults With Chronic Hepatitis B in North America

Marc G. Ghany, Wendy C. King, Mauricio Lisker‐Melman, Anna S.F. Lok, Norah Terrault, Harry L.A. Janssen, Mandana Khalili, Raymond T. Chung, William M. Lee, Daryl T.Y. Lau, Gavin A. Cloherty, Richard K. Sterling – 15 June 2021

Developing Priorities for Palliative Care Research in Advanced Liver Disease: A Multidisciplinary Approach

Arpan A. Patel, Christopher Woodrell, Nneka N. Ufere, Lissi Hansen, Puneeta Tandon, Manisha Verma, Jennifer Lai, Rachel Pinotti, Mina Rakoski, the Palliative Care Education, Advocacy, and Research in Liver Disease (PEARL) Workgroup and the AASLD Public Health / Healthcare Delivery Special Interest Group (SIG) – 15 June 2021 – Individuals with advanced liver disease (AdvLD), such as decompensated cirrhosis (DC) and hepatocellular carcinoma (HCC), have significant palliative needs.

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