Allan G. Redeker, M.D. (1924‐2021)
Tse‐Ling Fong, Jay H. Hoofnagle – 21 May 2021
Myeloid Endoplasmic Reticulum Resident Chaperone GP96 Facilitates Inflammation and Steatosis in Alcohol‐Associated Liver Disease
Anuradha Ratna, Arlene Lim, Zihai Li, Josepmaria Argemi, Ramon Bataller, Gabriela Chiosis, Pranoti Mandrekar – 21 May 2021 – Cellular stress–mediated chaperones are linked to liver macrophage activation and inflammation in alcohol‐associated liver disease (ALD). In this study, we investigate the role of endoplasmic reticulum (ER) resident stress chaperone GP96/HSP90B1/GRP94, paralog of the HSP90 family, in ALD pathogenesis. We hypothesize that ER resident chaperone, heat shock protein GP96, plays a crucial role in alcohol‐associated liver inflammation and contributes to liver injury.
How to Select Elderly Patients for Living Donor Liver Transplantation With Acceptable Outcomes
Kenei Furukawa, Koichiro Haruki, Tomohiko Taniai, Hironari Kawai, Toru Ikegami – 21 May 2021
REPLY:
Binu V. John, Yangyang Deng, Paul Martin, Cynthia Levy, Tamar H. Taddei, David E. Kaplan, Bassam Dahman – 21 May 2021
Letter to the Editor: Is Male Sex Associated With Increased Liver‐Related Mortality in Primary Biliary Cholangitis and Cirrhosis?
Li‐Yang Sun, Jia‐Yu Hu, Lei Liang, Xiang‐Min Tong, Dong‐Sheng Huang, Tian Yang – 21 May 2021
Lactic Acidosis, Hypoglycemia, and Eosinophilia: Novel Markers of Antibody‐Mediated Rejection Causing Graft Ischemia
James M. Halle‐Smith, Angus Hann, Owen L. Cain, M. Thamara P. R. Perera, Desley A. H. Neil – 20 May 2021
Type 2 Autoimmune Hepatitis and Nonadherence to Medication Correlate With Premature Birth and Risk of Postpartum Flare
Kathryn Olsen, James Hodson, Vincenzo Ronca, Amber G. Bozward, Jennifer Hayden, Grace Wootton, Matthew Armstrong, David H. Adams, Omar El‐Sherif, James Ferguson, Ellen Knox, Tracey Johnston, Fiona Thompson, Ye Htun Oo – 20 May 2021 – Autoimmune hepatitis (AIH) is an immune‐mediated chronic liver disease that affects all ages, including women of childbearing age. Optimal management during pregnancy is poorly defined.
Type 2 Autoimmune Hepatitis and Nonadherence to Medication Correlate With Premature Birth and Risk of Postpartum Flare
Kathryn Olsen, James Hodson, Vincenzo Ronca, Amber G. Bozward, Jennifer Hayden, Grace Wootton, Matthew Armstrong, David H. Adams, Omar El‐Sherif, James Ferguson, Ellen Knox, Tracey Johnston, Fiona Thompson, Ye Htun Oo – 20 May 2021 – Autoimmune hepatitis (AIH) is an immune‐mediated chronic liver disease that affects all ages, including women of childbearing age. Optimal management during pregnancy is poorly defined.
TIPS for Adults Without Cirrhosis With Chronic Mesenteric Venous Thrombosis and EHPVO Refractory to Standard‐of‐Care Therapy
Gabriel M. Knight, Jeffrey Clark, Justin R. Boike, Haripriya Maddur, Daniel R. Ganger, Abhinav Talwar, Ahsun Riaz, Kush Desai, Samdeep Mouli, Elias Hohlastos, Juan‐Carlos Garcia Pagan, Ahmed Gabr, Brady Stein, Robert Lewandowski, Bartley Thornburg, Riad Salem – 20 May 2021
Inpatient Frailty Assessment Is Feasible and Predicts Nonhome Discharge and Mortality in Decompensated Cirrhosis
Marina Serper, Sunny Y. Tao, Dorothea S. Kent, Patrik Garren, Alexander E. Burdzy, Jennifer C. Lai, Amir Gougol, Pamela M. Bloomer, K. Rajender Reddy, Michael A. Dunn, Andres Duarte‐Rojo – 20 May 2021 – Objective inpatient frailty assessments in decompensated cirrhosis are understudied. We examined the feasibility of inpatient frailty measurements and associations with nonhome discharge, readmission, and all‐cause mortality among patients admitted for cirrhosis complications. We conducted a prospective study at 3 liver transplantation (LT) centers.