The zinc finger and BTB domain containing protein ZBTB20 regulates plasma triglyceride metabolism by repressing lipoprotein lipase gene transcription in hepatocytes

Hao Li, Gan Liu, Xiaoqing Wan, Luting Zhou, Zhen‐Bang Qin, Xian‐Hua Ma, Kai Su, Ya‐Jin Liu, Jinghao Yuan, Chun‐Chun Wei, An‐Jing Ren, Yu‐Xia Chen, Stephen G. Young, Hai Zhang, Zhifang Xie, Weiping J. Zhang – 27 September 2021

Activation of p53 After Irradiation Impairs the Regenerative Capacity of the Mouse Liver

Makiko Urabe, Hayato Hikita, Yoshinobu Saito, Shinnosuke Kudo, Kenji Fukumoto, Naoki Mizutani, Yuta Myojin, Akira Doi, Katsuhiko Sato, Sadatsugu Sakane, Yuki Makino, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara – 27 September 2021 – Radiation therapy is one of the treatment methods for hepatocellular carcinoma. However, radiation tolerance of the liver is low, and the detailed effect of radiation on liver regeneration has not been clarified.

Seroconversion After Coronavirus Disease 2019 Vaccination in Patients Awaiting Liver Transplantation: Fact or Fancy?

Alberto Calleri, Margherita Saracco, Fabrizia Pittaluga, Rossana Cavallo, Renato Romagnoli, Silvia Martini – 25 September 2021 – Chronic liver disease increased the risk of severe coronavirus disease 2019 (COVID‐19). Trials to assess efficacy/safety of COVID‐19 vaccines in liver disease are underway. We evaluated the humoral immune response and safety of anti–COVID‐19 vaccination among patients waiting liver transplantation (LT). We enrolled all pre‐LT adults who completed anti‐COVID‐19 vaccination between January 2021‐August 2021 as study group.

Evaluating Outcomes Related to Donor and Recipient Metabolic Environment: Macrosteatotic Allografts and Nonalcoholic Steatohepatitis

Peter J. Altshuler, Hien Dang, Adam M. Frank, Ashesh P. Shah, Jaime Glorioso, Tingting Zhan, Arturo Rios Diaz, Osama Shaheen, Carlo B. Ramirez, Warren R. Maley, Adam S. Bodzin – 25 September 2021 – The increasing prevalence of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) affects both recipient and donor populations in liver transplantation. Presently, it is unclear whether transplantation of macrosteatotic allografts is affected by the metabolic milieu of liver transplant recipients.

The Prediction of In‐Hospital Mortality in Decompensated Cirrhosis with Acute‐on‐Chronic Liver Failure

Florence Wong, K. Rajender Reddy, Puneeta Tandon, Jennifer C. Lai, Nishita Jagarlamudi, Vanessa Weir, Beverley Kok, Sylvia Kalainy, Yanin T. Srisengfa, Somaya Albhaisi, Bradley Reuter, Chathur Acharya, Jawaid Shaw, Leroy R. Thacker, Jasmohan S. Bajaj – 25 September 2021 – Acute‐on‐chronic liver failure (ACLF) is a condition in cirrhosis associated with organ failure (OF) and high short‐term mortality.

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