LiverLearning®: 2021 Webinar: NASH as a Cause of Hepatocellular Carcinoma

Learn about epidemiology of NASH-HCC, differences in NASH-HCC compared to other etiologies and prevention and management of NASH-HCC. Presenters will discuss the rising burden of NASH-HCC such as its contribution to liver transplant, morbidity and mortality and cost. Along with differences in gender, presentation, prognosis and screening data, prevention, treatments such as resection versus liver transplant versus other therapies.Zobair M. Younossi Zobair M.

Developing Priorities for Palliative Care Research in Advanced Liver Disease: A Multidisciplinary Approach

Arpan A. Patel, Christopher Woodrell, Nneka N. Ufere, Lissi Hansen, Puneeta Tandon, Manisha Verma, Jennifer Lai, Rachel Pinotti, Mina Rakoski, the Palliative Care Education, Advocacy, and Research in Liver Disease (PEARL) Workgroup and the AASLD Public Health / Healthcare Delivery Special Interest Group (SIG) – 15 June 2021 – Individuals with advanced liver disease (AdvLD), such as decompensated cirrhosis (DC) and hepatocellular carcinoma (HCC), have significant palliative needs.

Comparison of HBV RNA and Hepatitis B Core Related Antigen With Conventional HBV Markers Among Untreated Adults With Chronic Hepatitis B in North America

Marc G. Ghany, Wendy C. King, Mauricio Lisker‐Melman, Anna S.F. Lok, Norah Terrault, Harry L.A. Janssen, Mandana Khalili, Raymond T. Chung, William M. Lee, Daryl T.Y. Lau, Gavin A. Cloherty, Richard K. Sterling – 15 June 2021

TNFAIP3 Interacting Protein 3 Is an Activator of Hippo‐YAP Signaling Protecting Against Hepatic Ischemia/Reperfusion Injury

Junjie Zhou, Manli Hu, Meiling He, Xiaoming Wang, Dating Sun, Yongping Huang, Xu Cheng, Jiajun Fu, Jie Cai, Tengfei Ma, Song Tian, Yufeng Hu, Fengjiao Hu, Dan Liu, Yanqi He, Lanlan Yan, Zhi‐Gang She, Xiao‐Jing Zhang, Yan‐Xiao Ji, Hui Liu, Hongliang Li, Hailong Yang, Peng Zhang – 15 June 2021

The Matrisome Genes From Hepatitis B–Related Hepatocellular Carcinoma Unveiled

Wei Chen, Romain Desert, Xiaodong Ge, Hui Han, Zhuolun Song, Sukanta Das, Dipti Athavale, Hong You, Natalia Nieto – 15 June 2021 – Chronic hepatitis B virus (HBV) infection changes the composition of the extracellular matrix (ECM) and enables the onset and progression of hepatocellular carcinoma (HCC). The ensemble of ECM proteins and associated factors is a major component of the tumor microenvironment. Our aim was to unveil the matrisome genes from HBV‐related HCC.

Chyme Reinfusion Restores the Regulatory Bile Salt–FGF19 Axis in Patients With Intestinal Failure

Kiran V.K. Koelfat, Denis Picot, Xinwei Chang, Mireille Desille‐Dugast, Hans M. Eijk, Sander M.J. Kuijk, Martin Lenicek, Sabrina Layec, Marie Carsin, Laurence Dussaulx, Eloi Seynhaeve, Florence Trivin, Laurence Lacaze, Ronan Thibault, Frank G. Schaap, Steven W.M. Olde Damink – 15 June 2021

Extensive Health Care Utilization and Costs of an Early Liver Transplantation Program for Alcoholic Hepatitis

Gene Y. Im, Alexander S. Vogel, Sander Florman, Jonathan Nahas, Scott L. Friedman, Sarah Aqui, Laura Ford, Omar Mirza, Leona Kim‐Schluger, Thomas D. Schiano – 15 June 2021 – Early liver transplantation (LT) for severe alcoholic hepatitis (AH) is a rescue therapy for highly selected patients with favorable psychosocial profiles not responding to medical therapy. Given the expected increase of AH candidate referrals requiring complex care and comprehensive evaluations, increased workload and cost might be expected from implementing an early LT program for AH but have not been determined.

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